Evidence map›Paper›PMID 31001540›Full record

ArticleFrontiers in cardiovascular medicine2019

Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.

Karima Ait-Aissa, James S Heisner, Laura E Norwood Toro, Dennis Bruemmer, Genevieve Doyon, Leanne Harmann, Aron Geurts, Amadou K S Camara, Andreas M Beyer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. How to measure and model cardiovascular aging.Cardiovascular research · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Cardiovascular aging: spotlight on mitochondria.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karima Ait-AissaCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
James S HeisnerDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Laura E Norwood ToroCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Dennis BruemmerVascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, United States.
Genevieve DoyonVascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, United States.
Leanne HarmannCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Aron GeurtsCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Amadou K S CamaraDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Andreas M BeyerCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Medical College of Wisconsin · USUniversity of Pittsburgh · US

Funding

Pivotal Role of Mitochondrial Telomerase in Regulation of Vascular Tone and Redox HomeostasisR01HL133029 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2017 to 2021
$2.2M
Differentiation of mitochondrial vs. nuclear function of telomeraseR21OD018306 · OD · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2014 to 2015
$411k
NHLBI NIH HHS R01 HL133029NIH HHS R21 OD018306
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

heart diseaseischema-reperfusion injurymitochondiareactive oxygen speciestelomerase (TERT)

Identifiers

PMID31001540
PMCPMC6454001
OpenAlexW2935503408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.