Evidence map›Paper›PMID 31001505›Full record

ArticleFrontiers in pediatrics2019

A Predictive Model of Postnatal Surgical Intervention in Children With Prenatally Detected Congenital Anomalies of the Kidney and Urinary Tract.

Mariana A Vasconcelos, Eduardo A Oliveira, Ana Cristina Simões E Silva, Cristiane S Dias, Robert H Mak, Carolina C Fonseca, Ana Paula M Campos, Ewout W Steyerberg, Yvonne Vergouwe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Mariana A VasconcelosPediatric Nephrology Unit, Department of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Eduardo A OliveiraPediatric Nephrology Unit, Department of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Ana Cristina Simões E SilvaPediatric Nephrology Unit, Department of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Cristiane S DiasPediatric Nephrology Unit, Department of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Robert H MakDivision of Pediatric Nephrology, Rady Children's Hospital San Diego, University of California, San Diego, San Diego, CA, United States.
Carolina C FonsecaDepartment of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Ana Paula M CamposDepartment of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Ewout W SteyerbergDepartment of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands.
Yvonne VergouweDepartment of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands.
Universidade Federal de Minas Gerais · BRErasmus MC · NLRady Children's Hospital-San Diego · US

Funding

National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2M
NICHD NIH HHS R24 HD050837
6 · The paper itself

Abstract

The aim of this study was to identify predictive factors and develop a model to assess individualized risk of postnatal surgical intervention in patients with antenatal hydronephrosis. This is a retrospective cohort study of 694 infants with prenatally detected congenital anomalies of kidney and urinary tract with a median follow-up time of 37 months. The main event of interest was postnatal surgical intervention. A predictive model was developed using Cox model with internal validation by bootstrap technique. Of 694 patients, 164 (24%) infants underwent surgical intervention in a median age of 7.8 months. Predictors of the surgical intervention in the model were: baseline glomerular filtration rate, associated hydronephrosis, presence of renal damage and the severity of renal pelvic dilatation. The optimism corrected c statistic for the model was 0.84 (95%CI, 0.82-0.87). The predictive model may contribute to identify infants at high risk for surgical intervention. Further studies are necessary to validate the model in patients from other settings.

Indexed as

antenatal hydronephrosiscongenital anomalies of kidney and urinary tractpredictive modelprenatal diagnosissurgical intervention

Identifiers

PMID31001505
PMCPMC6454042
OpenAlexW2930104506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.