ArticleCase reports in pediatrics2019
Neonatal Chylothoraces: A 10-Year Experience in a Tertiary Neonatal Referral Centre.
Article in Case reports in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 19 citations in OpenAlex.
- Milky pleural effusion in a neonate and approach to investigating chylothorax.BMJ case reports · 2021Article
- Non-immune hydrops fetalis secondary to congenital chylothorax with diffuse interstitial lung disease: a diagnostic conundrum.BMJ case reports · 2021Article
- Article
- Propranolol for the Treatment of Lymphatic Malformations in a Neonate - A Case Report and Review of Literature.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeonatal chylothorax is a rare condition, but has a high mortality. STUDY
objectivesTo analyse the outcomes of a series of neonates with chylothorax and review the literature to determine best practice.
designA case series review and a literature review using electronic databases including the key words neonates and chylothorax.
resultsSix cases of neonatal chylothorax were identified during a ten-year period, two had congenital chylothoraces and four iatrogenic chylothoraces after thoracic surgery or chest instrumentation. The neonates were ventilated for a median of 30 (range 13-125) days with a median maximum daily pleural fluid output of 218 (range 86-310) ml/kg/day. All the neonates were given medium-chain triglyceride (MCT) feeds which stabilised pleural fluid output in four and reduced it in another. Octreotide was used in three neonates, but the dosage used had no significant effect on pleural output. Two neonates required surgical intervention. The literature review demonstrated MCT feeds can reduce or stabilise pleural fluid output, but highlighted variable use of octreotide and inconsistent dosing regimens and outcomes. No consensus regarding indications for surgical intervention was identified. SUMMARY AND
conclusionNeonatal chylothorax is uncommon, but affected neonates require high healthcare utilisation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.