Evidence map›Paper›PMID 31001372›Full record

ArticleOxidative medicine and cellular longevity2019

Milk Fat Globule-Epidermal Growth Factor-Factor 8 Reverses Lipopolysaccharide-Induced Microglial Oxidative Stress.

Jie Li, Xiaotian Xu, Xiaoying Cai, Yinlun Weng, Yiping Wang, Qingyu Shen, Xiaolei Shi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  3. Spirulina (Nutrients · 2024
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  5. Review
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  7. Article
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  10. Review
  11. Article
  12. Article
  13. Cerebrospinal fluid MFG-E8 as a promising biomarker of amyotrophic lateral sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  14. Inhibitory Effects of Raw-ExtractMolecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jie LiDepartment of Neurology, Zengcheng District People's Hospital of Guangzhou, Guangzhou, China.
Xiaotian XuGuangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoying CaiDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yinlun WengDepartment of Neurosurgery, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Yiping WangDepartment of Neurosurgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Qingyu ShenDepartment of Neurology, Zengcheng District People's Hospital of Guangzhou, Guangzhou, China.
Xiaolei ShiDepartment of Neurology, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.ORCID 0000-0003-3707-6618
Sun Yat-sen University · CNFirst Affiliated Hospital of Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress plays an important role in various neurological disorders. Milk fat globule-epidermal growth factor-factor 8 (MFG-E8) is a regulatory protein for microglia. However, its involvement in microglial oxidative stress has not been established. In this study, we observed microglial oxidative stress in response to lipopolysaccharide (LPS) both

Indexed as

AnimalsAntigens, SurfaceGlycolipidsGlycoproteinsInflammationLipid DropletsLipopolysaccharidesMaleMiceMice, Inbred C57BLMicrogliaMilk ProteinsOxidative StressPrimary Cell CultureAntigens, SurfaceGlycolipidsGlycoproteinsLipopolysaccharidesMfge8 protein, mousemilk fat globuleMilk Proteins

Identifiers

PMID31001372
PMCPMC6436360
OpenAlexW2921463929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.