Evidence map›Paper›PMID 31001258›Full record

Trial reportFrontiers in immunology2019

Proinflammatory Cytokine Gene Polymorphisms in Bullous Pemphigoid.

Pardis-Sadat Tabatabaei-Panah, Hamideh Moravvej, Zahra Sadaf, Hadis Babaei, Maryam Geranmayeh, Sedigheh Hajmanouchehri, Ahmad Karimi, Fatemeh Sajjadi, Fereshteh Arghand, Ralf J Ludwig and 2 more

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid.Molecular genetics & genomic medicine · 2020
    Article
  9. The pathogenesis of bullous skin diseases.Journal of translational autoimmunity · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Pardis-Sadat Tabatabaei-PanahBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Hamideh MoravvejSkin Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra SadafBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Hadis BabaeiBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Maryam GeranmayehBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Sedigheh HajmanouchehriBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Ahmad KarimiBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Fatemeh SajjadiBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Fereshteh ArghandBiology Department, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Ralf J LudwigLübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Mareike WitteDepartment of Dermatology, University of Lübeck, Lübeck, Germany.
Reza AkbarzadehSkin Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Islamic Azad University South Tehran Branch · IRShahid Beheshti University of Medical Sciences · IRUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bullous pemphigoid (BP) is a rare autoimmune skin blistering disease, characterized by the presence of autoantibodies against hemidesmosomal autoantigens. Cytokine expression is altered in BP patients, and several of these differently expressed cytokines, including IL-1α, IL-1β, IL-8, and TNF-α, contribute to disease pathogenesis. Since genetic polymorphisms in the genes of these cytokines might be implicated in susceptibility to BP disease, we aimed at testing this implication in susceptibility to BP in an Iranian cohort. Blood samples were collected from the subjects and genomic DNA was extracted. To detect the single nucleotide polymorphisms (SNPs),

Indexed as

CytokinesPemphigoid, BullousPolymorphism, Single NucleotideAgedAged, 80 and overFemaleGene Expression ProfilingGene Expression RegulationHumansMaleMiddle AgedReverse Transcriptase Polymerase Chain ReactionCytokinesautoimmune diseasebullous pemphigoidgene expressiongene polymorphismproinflammatory cytokines

Identifiers

PMID31001258
PMCPMC6455081
OpenAlexW2925881118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.