ArticleFrontiers in neurology2019
Neuromusculoskeletal Simulation Reveals Abnormal Rectus Femoris-Gluteus Medius Coupling in Post-stroke Gait.
Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- A Longitudinal Study of Physical Function Factors Related to Lower Limb Circumduction During Gait in Acute Stroke Patients with Hemiparesis.Sensors (Basel, Switzerland) · 2025Article
- Muscle Synergies of the Lower Extremities During Gait Initiation in Individuals With and Without Chronic Ankle Instability.Journal of foot and ankle research · 2025Article
- Mechanisms of Post-stroke Stiff-Knee Gait: A Narrative Review.American journal of physical medicine & rehabilitation · 2025Review
- Does the rate of hip abductor and adductor muscle activation during weight transfer influence voluntary lateral stepping in chronic stroke?Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025Article
- An Evaluation Model for Brain Ischemia Protection in Mice by Low-Intensity Pulsed Ultrasound Stimulation Based on Functional Cortico-Muscular Coupling.Bioengineering (Basel, Switzerland) · 2025Article
- Does Gait Assistance Modulate Reflex Excitability in Those with Spasticity? A Preliminary Study.IEEE ... International Conference on Rehabilitation Robotics : [proceedings] · 2025Article
- Post-stroke Stiff-Knee gait: are there different types or different severity levels?Journal of neuroengineering and rehabilitation · 2025Article
- Article
- Biomechanical analysis of stair walking patterns and their implications for knee health in young males.Frontiers in public health · 2025Article
- Hip and Knee Joint Kinematics Predict Quadriceps Hyperreflexia in People with Post-stroke Stiff-Knee Gait.Annals of biomedical engineering · 2023Article
- Predictive simulation of single-leg landing scenarios for ACL injury risk factors evaluation.PloS one · 2023Article
- Relationship between gait quality measures and modular neuromuscular control parameters in chronic post-stroke individuals.Journal of neuroengineering and rehabilitation · 2021Article
- The effect of asymmetrical gait induced by unilateral knee brace on the knee flexor and extensor muscles.Medical & biological engineering & computing · 2021Article
- Isolating the energetic and mechanical consequences of imposed reductions in ankle and knee flexion during gait.Journal of neuroengineering and rehabilitation · 2021Article
- Rectus femoris hyperreflexia contributes to Stiff-Knee gait after stroke.Journal of neuroengineering and rehabilitation · 2020Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Post-stroke gait is often accompanied by muscle impairments that result in adaptations such as hip circumduction to compensate for lack of knee flexion. Our previous work robotically enhanced knee flexion in individuals post-stroke with Stiff-Knee Gait (SKG), however, this resulted in greater circumduction, suggesting the existence of abnormal coordination in SKG. The purpose of this work is to investigate two possible mechanisms of the abnormal coordination: (1) a reflex coupling between stretched quadriceps and abductors, and (2) a coupling between volitionally activated knee flexors and abductors. We used previously collected kinematic, kinetic and EMG measures from nine participants with chronic stroke and five healthy controls during walking with and without the applied knee flexion torque perturbations in the pre-swing phase of gait in the neuromusculoskeletal simulation. The measured muscle activity was supplemented by simulated muscle activations to estimate the muscle states of the quadriceps, hamstrings and hip abductors. We used linear mixed models to investigate two hypotheses: (H1) association between quadriceps and abductor activation during an involuntary period (reflex latency) following the perturbation and (H2) association between hamstrings and abductor activation after the perturbation was removed. We observed significantly higher rectus femoris (RF) activation in stroke participants compared to healthy controls within the involuntary response period following the perturbation based on both measured (H1,
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