Evidence map›Paper›PMID 31001140›Full record

ArticleFrontiers in physiology2019

Peritoneal Dialysis Vintage and Glucose Exposure but Not Peritonitis Episodes Drive Peritoneal Membrane Transformation During the First Years of PD.

Maria Bartosova, Betti Schaefer, Karel Vondrak, Peter Sallay, Christina Taylan, Rimante Cerkauskiene, Maria Dzierzega, Gordana Milosevski-Lomic, Rainer Büscher, Ariane Zaloszyc and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. Non-infectious complications of peritoneal dialysis in children.Pediatric nephrology (Berlin, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 8 countries.

Maria BartosovaCenter for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Betti SchaeferCenter for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Karel VondrakDepartment of Pediatrics, Motol University Hospital, Prague, Czechia.
Peter Sallay1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Christina TaylanPediatric Nephrology, Children's and Adolescent's Hospital, University Hospital of Cologne, Cologne, Germany.
Rimante CerkauskieneChildren's Clinic, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Maria DzierzegaDepartment of Pediatric Emergency, Medicine University Hospital, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
Gordana Milosevski-LomicNephrology Department, University Children's Hospital, Belgrade, Serbia.
Rainer BüscherPediatric Nephrology, University Children's Hospital, Essen, Germany.
Ariane ZaloszycDepartment of Pediatrics 1, Strasbourg University Hospital, Strasbourg, France.
Philipp RomeroDivision of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Felix LasitschkaDepartment of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Bradley A WaradyChildren's Mercy Kansas City, Kansas City, MO, United States.
Franz SchaeferCenter for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Akos UjszasziDivision of Nephrology, University Hospital Heidelberg, Heidelberg, Germany.
Claus Peter SchmittCenter for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEChildren's Mercy Hospital · USEssen University Hospital · DEJagiellonian University · PLSemmelweis University · HUUniversité de Strasbourg · FRUniversity Children's Hospital, Belgrade · RSUniversity Hospital Cologne · DEUniversity Hospital in Motol · CZVilnius University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of peritoneal dialysis (PD) associated peritonitis on peritoneal membrane integrity is incompletely understood. Children are particularly suited to address this question, since they are largely devoid of preexisting tissue damage and life-style related alterations. Within the International Peritoneal Biobank, 85 standardized parietal peritoneal tissue samples were obtained from 82 children on neutral pH PD fluids with low glucose degradation product (GDP) content. 37 patients had a history of peritonitis and 16 of the 37 had two or more episodes. Time interval between tissue sampling and the last peritonitis episode was 9 (4, 36) weeks. Tissue specimen underwent digital imaging and molecular analyses. Patients with and without peritonitis were on PD for 21.0 (12.0, 36.0) and 12.8 (7.3, 27.0) months (

Indexed as

EMTglucoseglucose degradation productsperitoneal dialysisperitoneal membraneperitonitisTGF-ßVEGF

Identifiers

PMID31001140
PMCPMC6455046
OpenAlexW2932455415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.