Evidence map›Paper›PMID 31001134›Full record

ArticleFrontiers in physiology2019

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation.

Robert Schleip, Giulio Gabbiani, Jan Wilke, Ian Naylor, Boris Hinz, Adjo Zorn, Heike Jäger, Rainer Breul, Stephanie Schreiner, Werner Klingler

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Robert SchleipDepartment of Neuroanesthesiology, Neurosurgical Clinic, Ulm University, Günzburg, Germany.
Giulio GabbianiDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Jan WilkeDepartment of Sports Medicine, Institute of Sport Science, Goethe University Frankfurt, Frankfurt, Germany.
Ian NaylorSchool of Pharmacy, University of Bradford, Bradford, United Kingdom.
Boris HinzLaboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, University of Toronto, Toronto, ON, Canada.
Adjo ZornFascia Research Group, Experimental Anesthesiology, Ulm University, Ulm, Germany.
Heike JägerDivision of Neurophysiology, Ulm University, Ulm, Germany.
Rainer BreulAnatomische Anstalt, Ludwig-Maximilians-Universität, München, Germany.
Stephanie SchreinerDivision of Neurophysiology, Ulm University, Ulm, Germany.
Werner KlinglerFascia Research Group, Experimental Anesthesiology, Ulm University, Ulm, Germany.
Universität Ulm · DEGoethe University Frankfurt · DELudwig-Maximilians-Universität München · DEQueensland University of Technology · AUUniversity of Bradford · GBUniversity of Geneva · CHUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fascial tissues form a ubiquitous network throughout the whole body, which is usually regarded as a passive contributor to biomechanical behavior. We aimed to answer the question, whether fascia may possess the capacity for cellular contraction which, in turn, could play an active role in musculoskeletal mechanics. Human and rat fascial specimens from different body sites were investigated for the presence of myofibroblasts using immunohistochemical staining for α-smooth muscle actin (

Indexed as

connective tissuecontractilitycontracturemyofibroblastsstiffness

Identifiers

PMID31001134
PMCPMC6455047
OpenAlexW2933489627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.