Evidence map›Paper›PMID 31000760›Full record

ArticleScientific reports2019

Anti-HERV-W

Magdalena Niegowska, Małgorzata Wajda-Cuszlag, Grażyna Stępień-Ptak, Joanna Trojanek, Jacek Michałkiewicz, Mieczysław Szalecki, Leonardo A Sechi

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Microorganisms · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Superantigens and SARS-CoV-2.Pathogens (Basel, Switzerland) · 2022
    Article
  10. Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.International journal of molecular sciences · 2021
    Review
  11. HERV-W andPathogens (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Evolutionary Medicine of Retroviruses in the Human Genome.The American journal of the medical sciences · 2019
    Review
  17. Review
  18. Article
  19. Presence ofMicroorganisms · 2019
    Article
  20. PtpA and PknG Proteins Secreted byJournal of inflammation research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Magdalena NiegowskaLaboratory of Microbiology, Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Małgorzata Wajda-CuszlagClinic of Endocrinology and Diabetology, Children's Memorial Health Institute, Warsaw, Poland.
Grażyna Stępień-PtakClinic of Endocrinology and Diabetology, Children's Memorial Health Institute, Warsaw, Poland.
Joanna TrojanekDepartment of Clinical Microbiology and Immunology, Children's Memorial Health Institute, Warsaw, Poland.
Jacek MichałkiewiczDepartment of Clinical Microbiology and Immunology, Children's Memorial Health Institute, Warsaw, Poland.
Mieczysław SzaleckiClinic of Endocrinology and Diabetology, Children's Memorial Health Institute, Warsaw, Poland.
Leonardo A SechiLaboratory of Microbiology, Department of Biomedical Sciences, University of Sassari, Sassari, Italy. sechila@uniss.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence points at the role that human endogenous retroviruses (HERVs) may play through the activation of genes integrated across the human genome. Although a variety of genetic/epigenetic mechanisms maintain most HERVs silenced, independent environmental stimuli including infections may transactivate endogenous elements favoring pathogenic conditions. Several studies associated exposures to Mycobacterium avium subsp. paratuberculosis (MAP) with increased anti-MAP seroreactivity in T1D patients. Here, we assessed humoral responses against HERV envelope antigens (HERV-K

Indexed as

AdolescentAntibodies, Anti-IdiotypicAutoantibodiesDiabetes Mellitus, Type 1Endogenous RetrovirusesEpitopesFemaleGene Products, envGenome, HumanHumansItalyMaleMycobacterium avium subsp. paratuberculosisParatuberculosisPeptidesPregnancy ProteinsAntibodies, Anti-IdiotypicAutoantibodiesEpitopesGene Products, envPeptidesPregnancy Proteinssyncytin

Identifiers

PMID31000760
PMCPMC6472397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.