Evidence map›Paper›PMID 31000754›Full record

ArticleScientific reports2019

The evaluation of monocyte lymphocyte ratio as a preoperative predictor in urothelial malignancies: a pooled analysis based on comparative studies.

Xuan Zhu, Shui-Qing Wu, Ran Xu, Yin-Huai Wang, Zhao-Hui Zhong, Lei Zhang, Xiao-Kun Zhao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Monocyte programming by cancer therapy.Frontiers in immunology · 2022
    Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xuan ZhuDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China.
Shui-Qing WuDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China.
Ran XuDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China.
Yin-Huai WangDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China. wangyinhuai@csu.edu.cn.
Zhao-Hui ZhongDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China.
Lei ZhangDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China.
Xiao-Kun ZhaoDepartment of Urology, The Second Xiangya Hospital, Central South University, Hunan Province, People's Republic of China. xiaokunzhao@csu.edu.cn.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, several studies have reported monocyte lymphocyte ratio (MLR) to predict prognosis in various tumors. Our study was performed to evaluate the association between preoperative MLR between prognostic variables in urothelial carcinoma patients. Systematic literature search was conducted in PubMed, Embase, Web of science. The correlation between preoperative MLR and overall survival (OS), cancer specific survival (CSS), disease free survival (DFS)/relapse free survival (RFS), progression free survival(PFS) was evaluated in urothelial carcinoma patients. Meanwhile, the association between MLR and clinicopathological characteristics was assessed. Finally, 12 comparative studies comprising a total of 6209 patients were included for pooled analysis. The hazard ratios (HRs), odds ratios (ORs)and 95% confidence intervals (CIs) were further analyzed as effect measures. The pooled results demonstrated that elevated preoperative MLR indicated unfavorable OS (HR = 1.29, 95%CI = 1.18-1.39, I

Indexed as

Biomarkers, TumorCarcinoma, Transitional CellDisease-Free SurvivalFemaleHumansLymphocytesMaleMonocytesNeoplasm Recurrence, LocalPrognosisProportional Hazards ModelsUrologic NeoplasmsUrotheliumBiomarkers, Tumor

Identifiers

PMID31000754
PMCPMC6472363
OpenAlexW2990668845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.