Evidence map›Paper›PMID 31000629›Full record

ArticleThe Journal of biological chemistry2019

Chemical footprinting and kinetic assays reveal dual functions for highly conserved eukaryotic tRNA

Ashanti O Matlock, Brian A Smith, Jane E Jackman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. A comparison ofbioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ashanti O MatlockFrom the Department of Chemistry and Biochemistry, Center for RNA Biology, and Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210.
Brian A SmithFrom the Department of Chemistry and Biochemistry, Center for RNA Biology, and Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210.
Jane E JackmanFrom the Department of Chemistry and Biochemistry, Center for RNA Biology, and Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210 jackman.14@osu.edu.ORCID 0000-0001-9291-8852
The Ohio State University · US

Funding

Molecular Mechanism and Biological Function of 3'-5' PolymerasesR01GM087543 · NIGMS · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2010 to 2019
$2.7M
Cellular, molecular, and biochemical sciences training grantT32GM086252 · NIGMS · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH, MUSIER-FORSYTH, KARIN M · 2011 to 2020
$2.0M
A Systems Biology Approach for Targeted Drug Discovery for LeishmaniasisR21AI127582 · NIAID · OHIO STATE UNIVERSITY · PI IBBA, MICHAEL, SATOSKAR, ABHAY R · 2017 to 2018
$401k
Typhoon FLA9500 Biomedical ImagerS10OD023582 · OD · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2017 to 2017
$144k
NIAID NIH HHS R21 AI127582NIGMS NIH HHS R01 GM087543NIGMS NIH HHS T32 GM086252NIH HHS S10 OD023582
6 · The paper itself

Abstract

tRNA

Indexed as

AnticodonBiocatalysisCatalytic DomainEvolution, MolecularHomeodomain ProteinsHumansKineticsMutagenesis, Site-DirectedNucleic Acid ConformationRecombinant ProteinsRNA, Transfer, HisAnticodonHomeodomain ProteinsRecombinant ProteinsRHOXF2 protein, humanRNA, Transfer, His3′-5′ polymeraseenzyme mechanismguanylyltransferaseGUG anticodonnoncanonical polymerasenucleic acid specificityRNA maturationRNA modificationRNA polymeraseRNA-protein interactionsite-directed mutagenesistransfer RNA (tRNA)translation

Identifiers

PMID31000629
PMCPMC6552426
OpenAlexW2935718073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.