ArticleBMC pulmonary medicine2019
Prognostic impact of the ratio of the main pulmonary artery to that of the aorta on chest computed tomography in patients with idiopathic pulmonary fibrosis.
Article in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Attenuation Levels of Lung Fields in Quantitative Computed Tomography Evaluation Are Associated With Overall Survival and the Incidence of Acute Exacerbation in Combined Pulmonary Fibrosis and Emphysema: A Single-Center Retrospective Observational Study.Health science reports · 2026Article
- AI-based pulmonary artery to ascending aorta ratio on non-contrast CT for pulmonary hypertension: diameter vs. volume assessment.European heart journal. Imaging methods and practice · 2026Article
- Honeycomb wall thickening during acute deterioration of idiopathic pulmonary fibrosis: clinical, imaging and prognostic characteristics.Journal of thoracic disease · 2026Article
- Radiomics derived from HRCT can predict mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis.Journal of thoracic disease · 2025Article
- Pulmonary artery and aortic enlargement predict postoperative survival outcomes in lung cancer.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Comorbidities' Effect on IPF: Pathogenesis and Management.Biomedicines · 2025Review
- Pulmonary hypertension associated with lung diseases.The European respiratory journal · 2024Review
- The association of radiologic right heart strain indices with the severity of pulmonary parenchymal involvement and prognosis in patients with COVID-19.Journal of cardiovascular and thoracic research · 2024Article
- The association between pulmonary artery enlargement and mortality in an Emergency Department population undergoing computed tomography pulmonary angiography.Pulmonary circulation · 2023Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn many clinical disorders, there is a relationship between the ratio of the diameter of the main pulmonary artery (mPA) to that of the aorta (Ao) on chest computed tomography (CT). The aim of this study was to determine if the mPA/Ao ratio at diagnosis is associated with the clinical characteristics and outcomes in patients with idiopathic pulmonary fibrosis (IPF).
methodsWe retrospectively reviewed the diameters of the pulmonary artery and aorta on chest CT, clinical characteristics, and results of other examinations in 303 patients at the time of initial diagnosis of IPF at our tertiary care center between 2011 and 2015. The primary outcomes were death and lung transplantation. The patients were followed up until June 2017.
resultsOne hundred and eight patients (35.6%) died and 58 (19.1%) underwent lung transplantation during follow-up. The mean mPA and Ao diameters were 28.3 mm and 34.0 mm, respectively, and the mean mPA/Ao ratio was 0.84. Thirty-one patients (10.2%) had an mPA/Ao ratio > 1.0 and 182 (60.1%) had an mPA/Ao ratio > 0.8. Patients with an mPA/Ao ratio > 0.8 had a lower DLco value than those with an mPA/Ao ratio ≤ 0.8. In Kaplan-Meier analysis, patients with an mPA/Ao ratio > 1.0 or > 0.8 had worse outcomes than those with an mPA/Ao ratio ≤ 1.0 and ≤ 0.8, respectively.
conclusionsA higher mPA/Ao ratio based on 1.0 and 0.8 is associated with unfavorable prognosis in patients with IPF.
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