Observational studyBMC neurology2019
Outcome prediction in disorders of consciousness: the role of coma recovery scale revised.
Observational study in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04445649 (Investigation of Prognostic Factors to Regain Consciousness in Neurological Early Rehabilitation), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Prognostic Factors to Regain Consciousness in Neurological Early Rehabilitation
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Predictive Factors for Successful Decannulation in Patients with Tracheostomies and Brain Injuries: A Systematic Review.Dysphagia · 2024Pooled it
- Neuroprognostication after cardiac arrest in patients without withdrawal of life-sustaining therapy: a prospective observational multicenter study.Critical care (London, England) · 2026Observational
- Multisensory integration in peripersonal space indexes consciousness states in sleep and disorders of consciousness.Cell reports. Medicine · 2026Article
- The swallow, a target to follow the restauration of consciousness in acquired brain injury.Journal of rehabilitation medicine · 2025Observational
- Incidence, causes and prognostic outcomes of acute coma: a nationwide population-based retrospective cohort study in Taiwan.BMJ open · 2025Article
- Differences in Coma Recovery Scale-Revised performance in an upright position versus lying position.Frontiers in neurology · 2025Article
- Exploring end-of-life decision-making in China for disorders of consciousness.Annals of medicine · 2024Article
- Explaining recovery from coma with multimodal neuroimaging.Journal of neurology · 2024Observational
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- Article
- Neuroimmune activation is associated with neurological outcome in anoxic and traumatic coma.Brain : a journal of neurology · 2024Article
- The integrity of thalamo-dorsolateral prefrontal cortex tract: a key factor in residual consciousness in disorders of consciousness patients.Frontiers in neurology · 2024Article
- Prognosis of patients with prolonged disorders of consciousness after brain injury: a longitudinal cohort study.Frontiers in public health · 2024Article
- Establishment and validation of a bad outcomes prediction model based on EEG and clinical parameters in prolonged disorder of consciousness.Frontiers in human neuroscience · 2024Article
- Coma Recovery Scale-Revised Predicts Disability Rating Scale in Acute Rehabilitation of Severe Traumatic Brain Injury.Archives of physical medicine and rehabilitation · 2023Article
- A functional near-infrared spectroscopy study on hemodynamic changes of patients with prolonged disorders of consciousness responding to different auditory stimuli.BMC neurology · 2023Article
- Machine learning and network analysis for diagnosis and prediction in disorders of consciousness.BMC medical informatics and decision making · 2023Article
- Sleep in Disorders of Consciousness: A Brief Overview on a Still under Investigated Issue.Brain sciences · 2023Review
- Clinical application of recommendations for neurobehavioral assessment in disorders of consciousness: an interdisciplinary approach.Frontiers in human neuroscience · 2023Review
- Predictors of long-term decannulation in patients with disorders of consciousness.Frontiers in neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the utility of the revised coma remission scale (CRS-r), together with other clinical variables, in predicting emergence from disorders of consciousness (DoC) during intensive rehabilitation care.
methodsData were retrospectively extracted from the medical records of patients enrolled in a specialized intensive rehabilitation unit. 123 patients in a vegetative state (VS) and 57 in a minimally conscious state (MCS) were included and followed for a period of 8 weeks. Demographical and clinical factors were used as outcome measures. Univariate and multivariate Cox regression models were employed for examining potential predictors for clinical outcome along the time.
resultsVS and MCS groups were matched for demographical and clinical variables (i.e., age, aetiology, tracheostomy and route of feeding). Within 2 months after admission in intensive neurorehabilitation unit, 3.9% were dead, 35.5% had a full recovery of consciousness and 66.7% remained in VS or MCS. Multivariate analysis demonstrated that the best predictor of functional improvement was the CRS-r scores. In particular, patients with values greater than 12 at admission were those with a favourable likelihood of emergence from DoC.
conclusionsOur study highlights the role of the CRS-r scores for predicting a short-term favorable outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.