Evidence map›Paper›PMID 30999791›Full record

ArticlePlant signaling & behavior2019

γ-Aminobutyric acid is closely associated with accumulation of flavonoids.

Tiantian Xie, Jing Ji, Wei Chen, Jianyun Yue, Changjian Du, Jiacheng Sun, Lanzhen Chen, Zeping Jiang, Shengqing Shi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant signaling & behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Acclimation Strategy of Masson Pine (International journal of molecular sciences · 2022
    Article
  2. C4 Bacterial Volatiles Improve Plant Health.Pathogens (Basel, Switzerland) · 2021
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tiantian Xiea State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Jing Jia State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Wei Chena State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Jianyun Yuea State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Changjian Dua State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Jiacheng Suna State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.
Lanzhen Chenb Institute of Apicultural Research , Chinese Academy of Agricultural Sciences , Beijing , China.
Zeping Jiangd Research Institute of Forest Ecology, Environment and Protection, Key Laboratory of Forest Ecology and Environment of State Forestry Administration , Chinese Academy of Forestry , Beijing , China.
Shengqing Shia State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.ORCID 0000-0002-5813-6707
Chinese Academy of Forestry · CNChinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

γ-Aminobutyric acid (GABA) is an important neurotransmitter in mammals whose receptor is reported to be regulated by flavonoids. In plants, it is considered to be at the intersection of carbon and nitrogen metabolism, but its relationship with flavonoid metabolism remains unclear. Our recent RNA-seq analysis showed that expression of flavonoid biosynthetic genes was influenced in poplar by the blockage of α-ketoglutarate dehydrogenase (α-KGDH) activity and the application of GABA under NaCl stress, accompanied by the changes in GABA shunt activity. Here, we further found that the flavonoid accumulation was significantly affected by blocking the activities of α-KGDH and GABA transaminase as well as applying exogenous GABA, coupled with the changes of endogenous GABA contents. Key genes involved in the flavonoid biosynthetic pathway were also significantly influenced, including two

Indexed as

Biosynthetic PathwaysFlavonoidsgamma-Aminobutyric AcidGene Expression Regulation, PlantPlant LeavesPopulusSeedlingsSuccinatesVigabatrinFlavonoidsgamma-Aminobutyric AcidSuccinatessuccinyl phosphateVigabatrincarbon metabolismflavonoidsGABAphenylpropanoid pathwaypoplar

Identifiers

PMID30999791
PMCPMC6619973
OpenAlexW2936758265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.