ArticleInternational journal of molecular sciences2019
Goeckerman Therapy of Psoriasis: Genotoxicity, Dietary Micronutrients, Homocysteine, and
Martin Beranek, Andrea Malkova, Zdenek Fiala, Jan Kremlacek, Kvetoslava Hamakova, Lenka Zaloudkova, Pavel Borsky, Tomas Adamus, Vladimir Palicka, Lenka Borska
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors at 3 institutions in 1 country.
Martin BeranekInstitute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, 50005 Hradec Kralove, Czech Republic. beranek@lfhk.cuni.cz.
Andrea MalkovaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, 50003 Hradec Kralove, Czech Republic. malka8ar@lfhk.cuni.cz.
Zdenek FialaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, 50003 Hradec Kralove, Czech Republic. fiala@lfhk.cuni.cz.
Jan KremlacekInstitute of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, 50003 Hradec Kralove, Czech Republic. kremlack@lfhk.cuni.cz.ORCID 0000-0001-8641-4287
Kvetoslava HamakovaClinic of Dermatology and Venereology, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech Republic. kveta.hamakova@fnhk.cz.
Lenka ZaloudkovaInstitute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, 50005 Hradec Kralove, Czech Republic. lenka.zaloudkova@fnhk.cz.
Pavel BorskyInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, 50003 Hradec Kralove, Czech Republic. borskyp@lfhk.cuni.cz.
Tomas AdamusDepartment of Biomedical Sciences, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic. Tomas.Adamus@osu.cz.
Vladimir PalickaInstitute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, 50005 Hradec Kralove, Czech Republic. palicka@lfhk.cuni.cz.
Lenka BorskaInstitute of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, 50003 Hradec Kralove, Czech Republic. borka@lfhk.cuni.cz.ORCID 0000-0002-8580-1485
Charles University · CZUniversity Hospital Hradec Králové · CZUniversity of Ostrava · CZ
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Goeckerman therapy (GT) of psoriasis vulgaris is based on the application of crude coal tar and ultraviolet radiation. We investigated DNA damage by the number of micronucleated binucleated cells (MNBC) in lymphocytes, serum homocysteine, vitamin B12, folic acid, and two polymorphisms (C677T and A1298C) in the
Indexed as
Polymorphism, Single NucleotideAdultCoal TarDNA DamageFolic AcidHomocysteineHumansKeratolytic AgentsMethylenetetrahydrofolate Reductase (NADPH2)Micronucleus TestsMicronutrientsMiddle AgedPsoriasisUltraviolet TherapyVitamin B 12Coal TarFolic AcidHomocysteineKeratolytic AgentsMethylenetetrahydrofolate Reductase (NADPH2)MicronutrientsMTHFR protein, humanVitamin B 12folic acidgenotoxicityGoeckerman therapyhomocysteinepsoriasisvitamin B12
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Goeckerman Therapy of Psoriasis: Genotoxicity, Dietary Micronutrients, Homocysteine, and · full record | OpenQuestion