Evidence map›Paper›PMID 30999683›Full record

ArticlePolymers2019

Statistical Properties of Lasso-Shape Polymers and Their Implications for Complex Lasso Proteins Function.

Pawel Dabrowski-Tumanski, Bartosz Gren, Joanna I Sulkowska

Abstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pawel Dabrowski-TumanskiCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland. p.dabrowski@cent.uw.edu.pl.ORCID 0000-0001-9412-1716
Bartosz GrenCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland. b.gren@cent.uw.edu.pl.
Joanna I SulkowskaCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland. jsulkowska@cent.uw.edu.pl.ORCID 0000-0003-2452-0724

Funding

European Molecular Biology Organization Installation Grant #2057Ministerstwo Nauki i Szkolnictwa Wyższego #0003/ID3/2016/64Narodowe Centrum Nauki #2012/07/E/NZ1/01900Narodowe Centrum Nauki #2016/21/N/NZ1/02848Narodowe Centrum Nauki #2017/24/T/NZ1/00490
6 · The paper itself

Abstract

The shape and properties of closed loops depend on various topological factors. One of them is loop-threading, which is present in complex lasso proteins. In this work, we analyze the probability of loop-threading by the tail and its influence on the shape of the loop measured by the radius of gyration, distention, asphericity, and prolateness. In particular, we show that the probability of a trivial lasso for phantom polymer is non-zero even for an infinite structure, as well as that the threading flattens the loop by restricting its motion in one dimension. These results are further used to show that there are fewer non-trivial protein lassos than expected and select potentially functional complex lasso proteins.

Indexed as

asphericitylassoprolatenessproteinsthreadingtopology

Identifiers

PMID30999683
PMCPMC6523798

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.