Evidence map›Paper›PMID 30999657›Full record

ReviewInternational journal of environmental research and public health2019

Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery.

Luigi Laino, Marco Cicciù, Luca Fiorillo, Salvatore Crimi, Alberto Bianchi, Giulia Amoroso, Ines Paola Monte, Alan Scott Herford, Gabriele Cervino

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  10. Use of nonacog beta pegol during surgery in persons with hemophilia B: a case series.Research and practice in thrombosis and haemostasis · 2023
    Article
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  19. Regenerative Surgery with Dental Implant Rehabilitation in a Haemophiliac Patient.TH open : companion journal to thrombosis and haemostasis · 2021
    Article
  20. Growth Factor Applied to Oral and Regenerative Surgery.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luigi LainoMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", 80100 Napoli, Italy. luigi.laino@unicampania.it.
Marco CicciùDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina, Italy. acromarco@yahoo.it.
Luca FiorilloMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", 80100 Napoli, Italy. lfiorillo@unime.it.
Salvatore CrimiDepartment of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania, Italy. torecrimi@gmail.com.
Alberto BianchiDepartment of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania, Italy. alberto.bianchi@unict.it.
Giulia AmorosoDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina, Italy. amoroso.giulia@hotmail.it.
Ines Paola MonteDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, 95125 Catania, Italy. inemonte@unict.it.
Alan Scott HerfordDepartment of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92350, USA. aherford@llu.edu.
Gabriele CervinoDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina, Italy. amoroso.giulia@hotmail.it.
University of Messina · ITUniversity of Catania · ITLoma Linda University · USUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHaemophilia is a disease of genetic origin, which causes a defect in blood coagulation. Under normal conditions, in the case of leakage from the blood vessels, the blood forms a clot that reduces or blocks the bleeding. This process involves the activation of several plasma proteins in a cascade-like species. Two of these proteins, produced in the liver, factor VIII and factor IX, are deficient or present a functional defect in people with haemophilia. Because of this deficit, the haemophiliacs easily suffer external and internal bleeding. Surgical treatment of these patients is to be observed, and often their treatment is delayed due to unclear guidelines and risks in treating these patients. The aim is to provide clear guidelines in the case of surgical treatment of these patients.

methodsIn this study, we have considered all the guidelines that refer to the gold-maxillofacial surgery, focusing on the literature of the last 10 years.

resultsSurely, this collection of guidelines will favor the choice of the clinician towards safer and predictable protocols. This study does not want to create a guideline but evaluates the literature of the last 10 years, and highlights the latest for the treatment of these patients., with the aim of informing the pathology and at the same time making the surgical maneuvers safer.

conclusionsDespite the research of literature has produced few results, it was nevertheless possible to draw up a guideline thanks to additional information extrapolated from textbooks and other scientific articles. According to the guidelines, it is possible to proceed to the treatment of these patients, if with appropriate therapy in a safe and risk-free manner.

Indexed as

Factor VIIIHemophilia AHumansOral Surgical ProceduresPractice Guidelines as TopicRisk FactorsF8 protein, humanFactor VIIIcoagulopathiesguidelineshaemophiliamaxillo-facialoralsurgery

Identifiers

PMID30999657
PMCPMC6518229
OpenAlexW2937543715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.