Evidence map›Paper›PMID 30999609›Full record

ArticlePharmaceutics2019

Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release.

Alessandra Adrover, Patrizia Paolicelli, Stefania Petralito, Laura Di Muzio, Jordan Trilli, Stefania Cesa, Ingunn Tho, Maria Antonietta Casadei

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Laponite-Based Nanomaterials for Drug Delivery.Advanced healthcare materials · 2022
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Alessandra AdroverDipartimento di Ingegneria Chimica, Materiali e Ambiente, Sapienza Universitá di Roma, Via Eudossiana 18, 00184 Rome, Italy. alessandra.adrover@uniroma1.it.ORCID 0000-0001-5939-740X
Patrizia PaolicelliDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. patrizia.paolicelli@uniroma1.it.ORCID 0000-0003-3941-2355
Stefania PetralitoDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. stefania.petralito@uniroma1.it.
Laura Di MuzioDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. laura.dimuzio@uniroma1.it.
Jordan TrilliDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. jordan.trilli@uniroma1.it.
Stefania CesaDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. stefania.cesa@uniroma1.it.ORCID 0000-0002-8649-0017
Ingunn ThoDepartment of Pharmacy, University of Oslo, 0316 Oslo, Norway. ingunn.tho@farmasi.uio.no.ORCID 0000-0003-4241-4183
Maria Antonietta CasadeiDipartimento di Chimica e Tecnologie del Farmaco, Sapienza Universitá di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. mariaantonietta.casadei@uniroma1.it.
Sapienza University of Rome · ITUniversity of Oslo · NO

Funding

Sapienza Università di Roma RM11715C536C02B1.
6 · The paper itself

Abstract

In this study, gellan gum (GG), a natural polysaccharide, was used to fabricate spherical porous beads suitable as sustained drug delivery systems for oral administration. GG was cross-linked with calcium ions to prepare polymeric beads. Rheological studies and preliminary experiments of beads preparation allowed to identify the GG and the CaCl

Indexed as

beadsgastrointestinal drug releasegellan gumionotropic gelationlaponitemodeling studypolymer/clay compositeswelling

Identifiers

PMID30999609
PMCPMC6523394
OpenAlexW2938130300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.