Evidence map›Paper›PMID 30999602›Full record

ArticleMarine drugs2019

Chlorophyll Derivatives from Marine Cyanobacteria with Lipid-Reducing Activities.

Sara Freitas, Natália Gonçalves Silva, Maria Lígia Sousa, Tiago Ribeiro, Filipa Rosa, Pedro N Leão, Vitor Vasconcelos, Mariana Alves Reis, Ralph Urbatzka

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

  1. UPLC-ESI-TOF-MS Profiling of Metabolome Alterations in Barley (Journal of agricultural and food chemistry · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Effect ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Marine SeagrassMarine drugs · 2020
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sara FreitasInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. sfreitas@ciimar.up.pt.
Natália Gonçalves SilvaInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. nsilva@ciimar.up.pt.
Maria Lígia SousaInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. msousa@ciimar.up.pt.
Tiago RibeiroInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. tribeiro@ciimar.up.pt.
Filipa RosaInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. frosa@ciimar.up.pt.
Pedro N LeãoInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. pleao@ciimar.up.pt.ORCID 0000-0001-5064-9164
Vitor VasconcelosInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. vmvascon@fc.up.pt.ORCID 0000-0003-3585-2417
Mariana Alves ReisInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. mreis@ciimar.up.pt.
Ralph UrbatzkaInterdisciplinary Center of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal. rurbatzka@ciimar.up.pt.ORCID 0000-0001-7476-9195
Universidade do Porto · PT

Funding

European Regional Development Fund NORTE-01-0145-FEDER-000035Fundação para a Ciência e a Tecnologia ERA-MBT/0001/2015Fundação para a Ciência e a Tecnologia SFRH/BD/108314/2015Fundação para a Ciência e a Tecnologia SFRH/BD/116009/2016Fundação para a Ciência e a Tecnologia SFRH/BPD/112287/2015Fundação para a Ciência e a Tecnologia UID/Multi/04423/2019
6 · The paper itself

Abstract

Marine organisms, particularly cyanobacteria, are important resources for the production of bioactive secondary metabolites for the treatment of human diseases. In this study, a bioassay-guided approach was used to discover metabolites with lipid-reducing activity. Two chlorophyll derivatives were successfully isolated, the previously described 13

Indexed as

3T3-L1 CellsAdipocytesAnimalsBrassicaCarrier ProteinsCell LineChlorellaChlorophyllCyanobacteriaFatty Acid Synthase, Type ILipid MetabolismLipolysisMicePPAR gammaSirtuin 1Spinacia oleraceaCarrier ProteinsChlorophyllFatty Acid Synthase, Type Imicrosomal triglyceride transfer proteinPPAR gammaSirtuin 1anti-obesity drugschlorophyll derivativesmurine pre-adipocytesPPARγzebrafish Nile red fat metabolism assay

Identifiers

PMID30999602
PMCPMC6520785
OpenAlexW2937509056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.