Evidence map›Paper›PMID 30999275›Full record

ArticleStem cell research2019

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation.

Yu-Lin Kuang, Antonio Munoz, Gilbert Nalula, Katherine E Santostefano, Valentina Sanghez, Gabriela Sanchez, Naohiro Terada, Aras N Mattis, Michelina Iacovino, Carlos Iribarren and 2 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Stem cell research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  8. Reporter Alleles in hiPSCs: Visual Cues on Development and Disease.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. A Model of iPSC-Derived Macrophages withInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Yu-Lin KuangChildren's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
Antonio MunozChildren's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
Gilbert NalulaChildren's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
Katherine E SantostefanoUniversity of Florida College of Medicine, 1395 Center Drive Box 100275, Gainesville, FL 32610, USA.
Valentina SanghezLos Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1123 W Carson Street, Torrance, CA 90502, USA.
Gabriela SanchezKaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA.
Naohiro TeradaUniversity of Florida College of Medicine, 1395 Center Drive Box 100275, Gainesville, FL 32610, USA.
Aras N MattisDepartment of Pathology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
Michelina IacovinoLos Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1123 W Carson Street, Torrance, CA 90502, USA.
Carlos IribarrenKaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA.
Ronald M KraussChildren's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
Marisa W MedinaChildren's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA. Electronic address: mwmedina@chori.org.
Kaiser Permanente · USThe Lundquist Institute · USUniversity of Florida · USMartin Luther King, Jr. Multi-Service Ambulatory Care Center · USUniversity of California, San Francisco · US

Funding

Pharmacogenomics of Statin TherapyP50GM115318 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RISCH, NEIL J. · 2015 to 2019
$14.0M
The Role of Phosphatidylinositides in Lipid MetabolismR01HL139902 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MEDINA, MARISA WONG · 2018 to 2021
$1.7M
A Stem Cell Tactic to Promote Personalized MedicineR24GM119977 · NIGMS · UNIVERSITY OF FLORIDA · PI TERADA, NAOHIRO · 2016 to 2018
$1.3M
NHLBI NIH HHS R01 HL139902NIGMS NIH HHS P50 GM115318NIGMS NIH HHS R24 GM119977
6 · The paper itself

Abstract

Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine. Increasingly, laboratories are creating their own banks of iPSCs derived from diverse donors. However, there are not yet standardized guidelines for qualifying these cell lines, i.e., distinguishing between bona fide human iPSCs, somatic cells, and imperfectly reprogrammed cells. Here, we report the establishment of a panel of 30 iPSCs from CD34

Indexed as

Cell DifferentiationAntigens, DifferentiationBiomarkersCells, CulturedEctodermHumansInduced Pluripotent Stem CellsLeukocytes, MononuclearAntigens, DifferentiationBiomarkersEctoderm markerHuman induced pluripotent stem cellNESTINPAX6Trilineage differentiation

Identifiers

PMID30999275
PMCPMC6570500
OpenAlexW2938638864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.