ArticleFEBS open bio2019
Sexual dimorphisms in the transcriptomes of murine salivary glands.
Article in FEBS open bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 26 citations in OpenAlex.
- Loss of TRPV4 impairs mucin secretion and salivary rheological properties in male mouse sublingual glands.Odontology · 2026Article
- Lysophosphatidic Acid (LPA) Salivary Species Detection and Whole-mount LPA Receptor Localization in Mouse Salivary Gland.bioRxiv : the preprint server for biology · 2026Article
- Gene Expansion and Regulatory Rewiring Shape Sex-Biased Evolution of the Mouse Submandibular Gland Secretome.bioRxiv : the preprint server for biology · 2026Article
- Fixation matters: duration in fixative prior to immunofluorescent analysis directly impacts macrophage visualization in epithelial tissues.Discovery immunology · 2026Article
- Regional atrophy, cellular plasticity, and regenerative potential in irradiated murine salivary glands.Acta oncologica (Stockholm, Sweden) · 2025Article
- A single dose of radiation elicits comparable acute salivary gland injury to fractionated radiation.Disease models & mechanisms · 2024Article
- Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation.Cell reports · 2024Article
- Harderian Gland Development and Degeneration in theJournal of developmental biology · 2024Article
- Epithelial NaComprehensive Physiology · 2024Review
- Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- High-Resolution Transcriptomic Landscape of the Human Submandibular Gland.Journal of dental research · 2023Article
- p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.Scientific reports · 2023Article
- Salivary gland function, development, and regeneration.Physiological reviews · 2022Review
- A Global Vista of the Epigenomic State of the Mouse Submandibular Gland.Journal of dental research · 2021Article
- Sex differences feed into nuclear receptor signaling along the digestive tract.Biochimica et biophysica acta. Molecular basis of disease · 2021Review
- The effect of sex on the mouse lens transcriptome.Experimental eye research · 2021Article
- Deregulation of the Kallikrein Protease Family in the Salivary Glands of the Sjögren's Syndrome ERdj5 Knockout Mouse Model.Frontiers in immunology · 2021Article
- Article
- Sex-dependent Regeneration Patterns in Mouse Submandibular Glands.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020Article
- Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands.Physiological reports · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Transcriptional profiling identified 933 sexually dimorphic genes out of the 14 371 protein-coding genes expressed in the three major murine salivary glands: parotid, sublingual, and submandibular. Most (89%) sex-specific genes were enriched in a single gland, while only 0.5% of the sexually dimorphic genes were enriched in all glands. The sublingual gland displayed a strong male sex bias (94% of sex-enriched genes), while a sex preference was not obvious in the parotid or submandibular glands. A subset of transcription factor genes was correlated with the expression of gland-specific, sex-enriched genes. Higher expression of Cftr chloride and Scnn1 sodium channels in the male submandibular correlated with greater NaCl reabsorption. In conclusion, adult salivary glands display sex- and gland-specific differences in gene expression that reflect their unique functional properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.