Evidence map›Paper›PMID 30997719›Full record

ReviewChembiochem : a European journal of chemical biology2019

RNA Dynamics by NMR Spectroscopy.

Maja Marušič, Judith Schlagnitweit, Katja Petzold

Abstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. TetrahedralJACS Au · 2026
    Article
  3. Article
  4. Article
  5. Nature communications · 2026
    Article
  6. Article
  7. Article
  8. Application of NMR to Large RNAs.Journal of molecular biology · 2025
    Review
  9. Selective [9-Chembiochem : a European journal of chemical biology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. UltrafastAnalytical chemistry · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maja MarušičDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solnavägen 9, 17177, Stockholm, Sweden.ORCID 0000-0001-6595-193X
Judith SchlagnitweitDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solnavägen 9, 17177, Stockholm, Sweden.ORCID 0000-0002-6372-428X
Katja PetzoldDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solnavägen 9, 17177, Stockholm, Sweden.ORCID 0000-0001-9470-0347

Funding

H2020 Marie Skłodowska-Curie Actions EU H2020 / Project No. 747446Ragnar Söderbergs stiftelse M91/14Stiftelsen för Strategisk Forskning CA14-0023Vetenskapsrådet 2014-04303
6 · The paper itself

Abstract

An ever-increasing number of functional RNAs require a mechanistic understanding. RNA function relies on changes in its structure, so-called dynamics. To reveal dynamic processes and higher energy structures, new NMR methods have been developed to elucidate these dynamics in RNA with atomic resolution. In this Review, we provide an introduction to dynamics novices and an overview of methods that access most dynamic timescales, from picoseconds to hours. Examples are provided as well as insight into theory, data acquisition and analysis for these different methods. Using this broad spectrum of methodology, unprecedented detail and invisible structures have been obtained and are reviewed here. RNA, though often more complicated and therefore neglected, also provides a great system to study structural changes, as these RNA structural changes are more easily defined-Lego like-than in proteins, hence the numerous revelations of RNA excited states.

Indexed as

Nucleic Acid ConformationAlgorithmsBase SequenceKineticsMagnetic Resonance SpectroscopyModels, ChemicalModels, MolecularNuclear Magnetic Resonance, BiomolecularRNARNAdynamicsmotionNMR spectroscopyrelaxationRNA

Identifiers

PMID30997719
PMCPMC6899578

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.