Evidence map›Paper›PMID 30997688›Full record

ReviewJPEN. Journal of parenteral and enteral nutrition2019

RW-2018-Research Workshop: The Effect of Nutrition on Epigenetic Status, Growth, and Health.

Michael Skinner, L H Lumey, Tom P Fleming, Carmen Sapienza, Cathrine Hoyo, Lucia Aronica, Jeff Thompson, Peter F Nichol

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JPEN. Journal of parenteral and enteral nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 3 countries.

Michael SkinnerCenter for Reproductive Biology School of Biological Sciences, Washington State University, Pullman, Washington, USA.
L H LumeyDepartment of Epidemiology Mailman School of Public Health, Columbia University Medical Center, New York, New York, USA.
Tom P FlemingDevelopmental Biology, Biological Sciences, University of Southampton, Southampton, United Kingdom.
Carmen SapienzaFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine Temple University Philadelphia, Philadelphia, Pennsylvania, USA.
Cathrine HoyoDepartment of Biological Sciences, Integrated Health Sciences Facility Core, Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA.
Lucia AronicaDepartment of Medicine, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, California, USA.
Jeff ThompsonGundersen Health System, Lacrosse, Wisconsin, USA.
Peter F NicholDepartment of Surgery, Division of Pediatric Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Columbia University Irving Medical Center · USGundersen Health System · USNorth Carolina State University · USStanford University · USTemple University · USUniversity of Southampton · GBWashington State University · USWisconsin Division of Public Health · US

Funding

ASPEN 2018 Research Workshop (RW)The Effect of Nutrition on Epigenetic Status, Growth and HealthR13HD094514 · NICHD · AMERICAN SOCIETY/PARENT & ENTERAL NUTRIT · PI NICHOL, PETER F · 2018 to 2018
$6k
NICHD NIH HHS R13 HD094514
6 · The paper itself

Abstract

The goal of the 2018 American Society for Parenteral and Enteral Nutrition (ASPEN) Research Workshop was to explore the influence of nutrition and dietary exposure to xenobiotics on the epigenome during critical periods in development and how these exposures influence both disease incidence and severity transgenerationally. A growing compendium of research indicates that the incidence and severity of common and costly human diseases may be influenced by dietary exposures and deficiencies that modify the epigenome. The greatest periods of vulnerability to these exposures are the periconception period and early childhood. Xenobiotics in the food chain, protein malnutrition, and methyl donor deficiencies could have a profound bearing on the risk of developing heart disease, diabetes, obesity, hypertension, and mental illness over multiple generations. The financial impact and the life burden of these diseases are enormous. These and other aspects of nutrition, epigenetics, and health are explored in this research workshop.

Indexed as

Health StatusAnimalsEpigenesis, GeneticHumansMiceNutritional Physiological PhenomenaNutritional StatusAvy mouseDOHaDepigeneticshormesismetabolic syndromemethylomenutritionprotein malnutritionxenobiotics

Identifiers

PMID30997688
PMCPMC6625918
OpenAlexW2939194927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.