Evidence map›Paper›PMID 30997601›Full record

ArticleArchives of pharmacal research2019

Three new ent-abietane diterpenoids from the roots of Euphorbia fischeriana and their cytotoxicity in human tumor cell lines.

Minghui Li, Fang He, Yuan Zhou, Meigui Wang, Pingde Tao, Qingmei Tu, Guanghui Lv, Xintao Chen

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Archives of pharmacal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Molecules (Basel, Switzerland) · 2021
    Review
  7. Integrated Strategy of UHPLC-Q-TOF-MS and Molecular Networking for Identification of Diterpenoids fromEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Minghui LiDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Fang HeDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Yuan ZhouDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Meigui WangDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Pingde TaoDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Qingmei TuDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Guanghui LvDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China. lvguanghui0725@163.com.
Xintao ChenDepartment of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People's Republic of China. m18772836076@163.com.
Taihe Hospital · CNHubei University of Medicine · CNHuazhong University of Science and Technology · CN

Funding

the Program for Foundation of Health and Family Planning Commission of Hubei Province WJ2017F079the Soft Science Project of Taihe Hospital 2017rkt12
6 · The paper itself

Abstract

Three new ent-abietane diterpenoids, termed fischerianoids A-C (1-3), were isolated and identified from the ethyl acetate extracts of roots of the medicinally valuable plant Euphorbia fischeriana. The planar and relative structures of 1-3 were established via high-resolution electrospray ionisation mass spectrometry and one- and two-dimensional nuclear magnetic resonance spectroscopic analyses, and the absolute configuration of 1 was further established via X-ray crystallography experiment. Compounds 1-3 showed selective inhibitory potency against certain human tumor cell lines with IC

Indexed as

AbietanesAntineoplastic Agents, PhytogenicCell Line, TumorDrug Screening Assays, AntitumorEuphorbiaHumansPlant RootsAbietanesAntineoplastic Agents, PhytogenicCytotoxicityent-Abietane diterpenoidsEuphorbia fischerianaStructural elucidation

Identifiers

PMID30997601
PMCPMC6562045
OpenAlexW2937407149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.