Evidence map›Paper›PMID 30997592›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019

Tonic pupils: an unusual autonomic involvement in chronic inflammatory demyelinating polyneuropathy (CIDP).

Marcio Luiz Escorcio-Bezerra, Gilberto Mastrocola Manzano, Denis Bernardi Bichuetti, Karlo Faria Nunes, Daniele Sales Alves Correa, Acary Souza Bulle Oliveira, Alex Machado Baeta

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Adie's Pupil: A Diagnostic Challenge for the Physician.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Review
  3. Rare Neurologic Diseases and Neurological Sciences: a report for the celebration of the 2020 Rare Diseases Day.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marcio Luiz Escorcio-BezerraDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil. marciobzrra@gmail.com.ORCID http://orcid.org/0000-0002-2417-1061
Gilberto Mastrocola ManzanoDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Denis Bernardi BichuettiDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Karlo Faria NunesDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Daniele Sales Alves CorreaDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Acary Souza Bulle OliveiraDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Alex Machado BaetaDepartment of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic inflammatory demyelinating polyneuropathy (CIDP) is a neuropathy which affects mainly large myelinated axons and has a typically mild autonomic dysfunction mainly from postganglionic nerve fiber involvement. CASE REPORT: We report here an acute onset CIDP initially diagnosed as Guillain-Barré syndrome (GBS), unresponsive to treatment with intravenous immunoglobulin (IVIg), which later responded to plasmapheresis and corticoids. The patient had a markedly distal demyelination, prominent cranial nerve involvement and, interestingly, bilateral fixed dilated pupils. Despite complete clinical recovery, this neurological sign remained.

conclusionsTonic pupils have previously been described in different neurologic conditions, including GBS, but not yet in acute onset CIDP or in variants with predominantly distal demyelination. It differs from the classical Adie's pupil because it lacks the light-near dissociation. This case report expands the range of possible autonomic signs in acute onset CIDP, which could help physicians establish optimal treatment strategies earlier on.

Indexed as

Diagnostic ErrorsFemaleGuillain-Barre SyndromeHumansPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingTonic PupilYoung AdultAdie’s pupilAutonomic dysfunctionChronic inflammatory demyelinating polyneuropathyCIDPGuillain-Barré syndromeTonic pupil

Identifiers

PMID30997592
OpenAlexW2939783121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.