ArticleInternational archives of occupational and environmental health2019
Evaluation of heat stress and cumulative incidence of acute kidney injury in sugarcane workers in Guatemala.
Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cooling intervention studies among outdoor occupational groups: A review of the literature.American journal of industrial medicine · 2020Pooled it
- Hydration Interventions Among Agricultural Workers: A Pilot Study.Journal of occupational and environmental medicine · 2022Trial
- Longitudinal assessment of kidney function in migrant farm workers.Environmental research · 2021Trial
- Trends in Occupational Heat-Health Research in Low-and Middle-Income Countries: A Mapping Review.Current environmental health reports · 2026Review
- Association between ambient temperature and acute kidney injury: a nationwide space-time-stratified case-crossover study in Japan.Journal of exposure science & environmental epidemiology · 2026Article
- Kidney health among adolescents living in a high-risk region for CKDu.BMC nephrology · 2026Article
- Disparity in the regulation and prevention of water versus sodium imbalance in heat-stress nephropathy: a phylogenetic perspective.Clinical kidney journal · 2026Review
- Nuclear Magnetic Resonance-Based Urinary Metabolic Profiling for Assessing Heat Stress-Related Incident Kidney Injury in Health-Care Workers.GeoHealth · 2026Article
- An innovative method of evaluating the association of heat exposure and heart rate variability in a panel of agricultural workers with small and lightweight personal sensors.Journal of exposure science & environmental epidemiology · 2026Article
- Evaluating the effects of heat strain and air pollution on kidney health.Environment international · 2026Article
- Leveraging wearables to safeguard workers in a hotter climate.Frontiers in public health · 2026Article
- Longitudinal associations and interactions of heat and metal(loid) exposure with kidney outcomes in Mexican agricultural workers.Environmental research · 2025Article
- Longitudinal Estimated GFR Trajectories Among Workers at High Risk for CKD of Unknown Etiology.Kidney international reports · 2025Article
- Article
- Understanding Changes in Serum Creatinine During Work in Heat.Kidney international reports · 2025Article
- Heat Exposure and Short-Term Changes in Kidney Biomarkers: Answers to the CKD of Unknown Etiology Conundrum?Kidney international reports · 2025Article
- Heat exposure, heat strain, and off-work recovery of Guatemalan sugarcane workers.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Airborne particulate matter exposure in male sugarcane workers at risk for chronic kidney disease in Guatemala.Annals of work exposures and health · 2025Article
- Urology on a changing planet: links between climate change and urological disease.Nature reviews. Urology · 2025Review
- The work-recovery cycle of kidney strain and inflammation in sugarcane workers following repeat heat exposure at work and at home.European journal of applied physiology · 2025Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
Abstract
objectiveAgricultural workers worldwide exposed to heat stress could be at the risk of kidney injury, which could lead to chronic kidney disease of an unknown origin (CKDu). Hydration has been promoted as a key measure to reduce kidney injury. In the presence of a hydration intervention, the incidence of acute kidney injury (AKI) was calculated in a sugarcane worker population in Guatemala and several risk factors were evaluated.
methodsWe measured kidney function at the beginning and end of the work shift at three time points in 517 sugarcane workers. We defined AKI as an increase in serum creatinine of 26.5 µmol/L or 50% or more from the pre-shift value. Associations between AKI and risk factors were examined, including interactions with hydration status.
resultsThe prevalence of dehydration post-shift (> 1.020 specific gravity) was 11% in February, 9% in March, and 6% in April. Cumulative incidence of AKI was 53% in February, 54% in March, and 51% in April. AKI was associated with increasing post-shift specific gravity, a dehydration marker, (OR 1.24, 95% CI 1.02-1.52) and with lower electrolyte solution intake (OR 0.94, 95% CI 0.89-0.99).
conclusionsDehydration and insufficient electrolyte consumption are risk factors for AKI. However even well-hydrated sugarcane workers routinely experience AKI. While hydration is important and protective, there is a need to understand other contributors to risk of AKI and identify prevention strategies with these workers.
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