Evidence map›Paper›PMID 30997411›Full record

Trial reportBMJ open quality2019

Reducing inappropriate outpatient antibiotic prescribing: normative comparison using unblinded provider reports.

Richard V Milani, Jonathan K Wilt, Jonathan Entwisle, Jonathan Hand, Pedro Cazabon, Jefferson G Bohan

Open access · goldAbstract readControlled Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMJ open quality, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Cost to implement an outpatient stewardship intervention for acute otitis media (AOM).Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
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  7. Review
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  16. Designing Communication Feedback Systems To Reduce Healthcare Providers' Implicit Biases In Patient Encounters.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
    Article
  17. Article
  18. Simple optical nanomotion method for single-bacterium viability and antibiotic response testing.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Richard V MilaniCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Jonathan K WiltCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Jonathan EntwisleCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Jonathan HandCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Pedro CazabonCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Jefferson G BohanCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.
Ochsner Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Antibiotic resistance is a global health issue. Up to 50% of antibiotics are inappropriately prescribed, the majority of which are for acute respiratory tract infections (ARTI). Objective: To evaluate the impact of unblinded normative comparison on rates of inappropriate antibiotic prescribing for ARTI. Design: Non-randomised, controlled interventional trial over 1 year followed by an open intervention in the second year. Setting: Primary care providers in a large regional healthcare system. Participants: The test group consisted of 30 primary care providers in one geographical region; controls consisted of 162 primary care providers located in four other geographical regions. Intervention: The intervention consisted of provider and patient education and provider feedback via biweekly, unblinded normative comparison highlighting inappropriate antibiotic prescribing for ARTI. The intervention was applied to both groups during the second year. Main outcomes and measures: Rate of inappropriate antibiotic prescription for ARTI. Results: Baseline inappropriate antibiotic prescribing for ARTI was 60%. After 1 year, the test group rate of inappropriate antibiotic prescribing decreased 40%, from 51.9% to 31.0% (p<0.0001), whereas controls decreased 7% (61.3% to 57.0%, p<0.0001). In year 2, the test group decreased an additional 47% to an overall prescribing rate of 16.3%, and the control group decreased 40% to a prescribing rate of 34.5% after implementation of the same intervention. Conclusions and relevance: Provider and patient education followed by regular feedback to provider via normative comparison to their local peers through unblinded provider reports, lead to reductions in the rate of inappropriate antibiotic prescribing for ARTI and overall antibiotic prescribing rates.

Indexed as

PhysiciansAdultAnti-Bacterial AgentsFemaleHumansInappropriate PrescribingMaleMiddle AgedOutpatientsPractice Patterns, Physicians'Primary Health CareRespiratory Tract InfectionsAnti-Bacterial Agentsantibiotic managementdecision makingevidence-based medicine

Identifiers

PMID30997411
PMCPMC6440589
OpenAlexW2912077058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.