ArticleBMJ open ophthalmology2019
Bandage contact lens and topical steroids are risk factors for the development of microbial keratitis after epithelium-off CXL.
Article in BMJ open ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Corneal collagen cross-linking for bacterial infectious keratitis.The Cochrane database of systematic reviews · 2020Pooled it
- Early findings in a randomised controlled trial on crosslinking protocols using isoosmolar and hypoosmolar riboflavin for the treatment of progressive keratoconus.Acta ophthalmologica · 2025Trial
- Three-year results of accelerated transepithelial cross-linking (30 mW/cmBMJ open ophthalmology · 2022Trial
- Insights into the clinical presentation, imaging, and management of infiltrative keratitis following accelerated corneal collagen cross-linking.Indian journal of ophthalmology · 2026Observational
- Bacterial and fungal keratitis in Northeast Mexico: demographic, predisposing, and microbiological differences among non-contact lens, optical contact lens, and bandage contact lens wearers.International ophthalmology · 2026Observational
- Visual Recovery with Cryopreserved Amniotic Membrane After Epi-Off Corneal Cross-Linking in Keratoconus Patients: A Non-Randomized, Controlled, Retrospective Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Delayed onset Aspergillus niger keratitis post-DALK associated with bandage contact lens: a case report highlighting the importance of vigilant postoperative care and management.GMS ophthalmology cases · 2025Article
- Severe Complications after Corneal Collagen Cross-Linking (CXL).Klinische Monatsblatter fur Augenheilkunde · 2023Article
- Current clinical practice in corneal crosslinking for treatment of progressive keratoconus in four Nordic countries.Acta ophthalmologica · 2023Article
- Evaluation of a Post-Operative Therapy Protocol after Epithelium-Off Corneal Cross-Linking in Patients Affected by Keratoconus.Journal of clinical medicine · 2022Article
- A case of infectious crystalline keratopathy after corneal cross-linking.American journal of ophthalmology case reports · 2021Article
- Review
- Commentary: Recent advances in endothelial keratoplasty and the postoperative use of bandage contact lens.Indian journal of ophthalmology · 2021Article
- Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases.Frontiers in pharmacology · 2021Review
- Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against Pseudomonas aeruginosa.Investigative ophthalmology & visual science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the role of bandage contact lenses (BCL) and topical steroids as risk factors for the development of microbial keratitis after epithelium-off corneal collagen cross-linking (CXL). METHODS AND ANALYSIS: Patients undergoing CXL between February 2011 and July 2017 were included. Patients were divided into two groups: those who were treated postoperatively with a BCL, topical antimicrobial and steroids (group 1) and those who received only a topical antimicrobial until healing of the epithelial defect before introduction of topical steroids (group 2).
results1273 eyes of 964 patients were included. Group 1 comprised 316 eyes and group 2 comprised 957 eyes. There were no significant differences in the presence of persisting corneal haze or scarring between the two groups (p=0.57). Microbial keratitis occurred in nine eyes (0.71% of eyes) of eight (0.83%) patients (one case was bilateral) out of 1273 eyes.
conclusionThe use of BCL and topical steroids prior to healing of the epithelium is a significant risk factor for microbial keratitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.