ReviewInternational journal of women's dermatology2019
Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment.
Review in International journal of women's dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Familial Frontal Fibrosing Alopecia: Report of a case and systematic review of the literature.Sultan Qaboos University medical journal · 2021Pooled it
- FFA Patient Profile Analysis Based on the Authors' Observations and a Review of the Literature-An Original Survey.Journal of clinical medicine · 2025Article
- The 100 Most-Cited Publications in Lichen Planopilaris: A Bibliometric Analysis.Skin appendage disorders · 2025Article
- Clinical and demographic characteristics of frontal fibrosing alopecia in a dermatology referral center in Bogota, Colombia: a descriptive cross-sectional study.International journal of women's dermatology · 2024Article
- Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris.Postepy dermatologii i alergologii · 2024Article
- The Frontal Fibrosing Alopecia Treatment Dilemma.Journal of clinical medicine · 2024Review
- JAK Inhibitors in the Treatment of Lichen Planopilaris.Skin appendage disorders · 2024Review
- Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development.Journal of personalized medicine · 2024Review
- Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospective Study.Iranian journal of pathology · 2024Article
- Recalcitrant lichen planus pigmentosus treated with topical ruxolitinib.JAAD case reports · 2023Article
- Janus kinase inhibition for the treatment of refractory frontal fibrosing alopecia: A case series and review of the literature.JAAD case reports · 2023Article
- mTOR signaling in hair follicle and hair diseases: recent progress.Frontiers in medicine · 2023Review
- Frontiers in Lichen Planopilaris and Frontal Fibrosing Alopecia Research: Pathobiology Progress and Translational Horizons.JID innovations : skin science from molecules to population health · 2022Review
- Extensive facial scarring after ablative laser resurfacing in a patient with frontal fibrosing alopecia.JAAD case reports · 2022Article
- [Frontal fibrosing alopecia-update].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022Review
- Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.Biomedicines · 2021Article
- A Novel Atypical Presentation of Frontal Fibrosing Alopecia Involving the Frontoparietal Scalp.Skin appendage disorders · 2020Article
- Ocrelizumab-induced alopecia areata-A series of five patients from Ontario, Canada: A case report.SAGE open medical case reports · 2020Article
- Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide.Clinical, cosmetic and investigational dermatology · 2020Review
- COVID-19: The experience from Iran.Clinics in dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles in the pathogenesis and progression of FFA. Because of several differences in clinical manifestations, response to treatments, and pathological findings, these two conditions could be differentiated from each other. Taking into account the already discussed signaling pathways and involved players such as T cells, mast cells, and sebaceous glands, different possible therapeutic options could be suggested. In addition to treatments supported by clinical evidence, such as 5 alpha-reductase inhibitors, topical calcineurin inhibitors, hydroxychloroquine, peroxisome proliferator-activated receptor gamma agonists, and oral retinoid agents, various other treatment strategies and drugs, such as phototherapy, Janus kinase inhibitors, dehydroepiandrosterone, sirolimus, cetirizine, and rituximab, could be suggested to mitigate disease progression. Of course, such lines of treatment need further evaluation in clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.