Evidence map›Paper›PMID 30997369›Full record

ArticleBone reports2019

Calcium isotope ratios in blood and urine: A new biomarker for the diagnosis of osteoporosis.

A Eisenhauer, M Müller, A Heuser, A Kolevica, C-C Glüer, M Both, C Laue, U V Hehn, S Kloth, R Shroff and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 70 citations in OpenAlex.

  1. Uranium Isotopes: From Geosciences to Biomedical Sciences.Current environmental health reports · 2026
    Review
  2. Review
  3. Bone turnover markers in the management of CKD-associated osteoporosis-a European consensus.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  4. Calcium isotope ratio (δOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

A EisenhauerGEOMAR Helmholtz Centre for Ocean Research Kiel, 24148 Kiel, Wischhofstr.1-3, Germany.
M MüllerUniversity Medical Center Schleswig-Holstein (UKSH), Arnold-Heller-Str. 3, 24105 Kiel, Germany.
A HeuserGEOMAR Helmholtz Centre for Ocean Research Kiel, 24148 Kiel, Wischhofstr.1-3, Germany.
A KolevicaGEOMAR Helmholtz Centre for Ocean Research Kiel, 24148 Kiel, Wischhofstr.1-3, Germany.
C-C GlüerSektion Biomedizinische Bildgebung, Klinik für Radiologie und Neuroradiologie, Am Botanischen Garten 14, 24118 Kiel, Germany.
M BothKlinik für Neuroradiologie und Radiologie, (UKSH), Arnold-Heller-Str. 3, 24105 Kiel, Germany.
C LaueClinical Research Center Kiel GmbH, Schauenburgerstraße 116, 24118 Kiel, Germany.
U V HehnMedistat, GmbH, Kieler Straße 15, 24119 Kronshagen, Germany.
S KlothOSTEOLABS GmbH, c/o GEOMAR Helmholtz Centre for Ocean Research Kiel, 24148 Kiel, Wischhofstr.1-3, Germany.
R ShroffGreat Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, United Kingdom of Great Britain and Northern Ireland.
J SchrezenmeirClinical Research Center Kiel GmbH, Schauenburgerstraße 116, 24118 Kiel, Germany.
GEOMAR Helmholtz Centre for Ocean Research Kiel · DEClinical Research Center Kiel · DEGreat Ormond Street Hospital for Children NHS Foundation Trust · GBSchauenburg (Germany) · DESchmerzklinik Kiel · DE

Funding

Department of Health CDF-2016-09-038
6 · The paper itself

Abstract

We assessed the potential of Calcium (Ca) isotope fractionation measurements in blood (δ

Indexed as

Bone biomarkersBone mineral density (BMD)Calcium isotopesDual energy x-ray absorptiometry (DXA)Mass-spectrometryOsteoporosis

Identifiers

PMID30997369
PMCPMC6453776
OpenAlexW2922422421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.