Evidence map›Paper›PMID 30997344›Full record

ArticleMolecular genetics and metabolism reports2019

Influence of genetic copy number variants of the human GLUT3 glucose transporter gene

Kim R Simpfendorfer, Wentian Li, Andrew Shih, Hongxiu Wen, Harini P Kothari, Edward A Einsidler, Arthur Wuster, Julie Hunkapiller, Timothy W Behrens, Robert R Graham and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Kim R SimpfendorferRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Wentian LiRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Andrew ShihRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Hongxiu WenRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Harini P KothariRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Edward A EinsidlerRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Arthur WusterDepartment of Human Genetics, Genentech Inc., 1 DNA Way, South San Francisco, California, USA.
Julie HunkapillerDepartment of Human Genetics, Genentech Inc., 1 DNA Way, South San Francisco, California, USA.
Timothy W BehrensDepartment of Human Genetics, Genentech Inc., 1 DNA Way, South San Francisco, California, USA.
Robert R GrahamDepartment of Human Genetics, Genentech Inc., 1 DNA Way, South San Francisco, California, USA.
Michael J TownsendDepartment of Biomarker Discovery OMNI, Genentech Inc., 1 DNA Way, South San Francisco, California, USA.
Doron M BeharGene by Gene, Genomic Research Center, Houston, TX, USA.
Rui HuGene by Gene, Genomic Research Center, Houston, TX, USA.
Elliott GreenspanGene by Gene, Genomic Research Center, Houston, TX, USA.
Peter K GregersenRobert S. Boas Center for Genomics and Human Genetics, the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, USA.
Feinstein Institute for Medical Research · USDonald & Barbara Zucker School of Medicine at Hofstra/Northwell · US

Funding

The role of GLUT3 in the genetics of autoimmunity and immunometabolismK01AR071502 · NIAMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SIMPFENDORFER, KIM R · 2018 to 2022
$639k
6 · The paper itself

Abstract

objectivesThe gene encoding glucose transporter 3 (GLUT3,

methodsCells from genotyped healthy controls were analyzed for

resultsHeterozygous deletion of

conclusionsDespite a robust

Indexed as

Copy number variantDeletionGlucose transportGLUT3GlycolysisRheumatoid arthritisSLC2A3

Identifiers

PMID30997344
PMCPMC6453668
OpenAlexW2929071180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.