Evidence map›Paper›PMID 30997140›Full record

ArticleBMJ open gastroenterology2019

Haemostasis treatment using dual red imaging during endoscopic submucosal dissection: a multicentre, open-label, randomised controlled trial.

Ai Fujimoto, Yutaka Saito, Seiirhicro Abe, Shu Hoteya, Kosuke Nomura, Hiroshi Yasuda, Yasumasa Matsuo, Toshio Uraoka, Shiko Kuribayashi, Itaru Saito and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMJ open gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Utility of red dichromatic imaging for identifying the bleeding point in endoscopic hemostasis of colonic diverticular bleeding.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Endoscopic submucosal dissection of early-stage rectal cancer using full-time red dichromatic imaging to minimize and avoid significant bleeding.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Ai FujimotoDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-3489-3356
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Seiirhicro AbeEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Shu HoteyaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Kosuke NomuraDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Hiroshi YasudaDivision of Gastroenterology and Hepatology, St Marianna University School of Medicine, Kawasaki, Japan.
Yasumasa MatsuoDivision of Gastroenterology and Hepatology, St Marianna University School of Medicine, Kawasaki, Japan.
Toshio UraokaDepartment of Gastroenterology and Hepatology, Gunma University, Maebashi, Japan.
Shiko KuribayashiDepartment of Gastroenterology and Hepatology, Gunma University, Maebashi, Japan.
Itaru SaitoDepartment of Endoscopy and Endoscopic Surgery, The University of Tokyo, Tokyo, Japan.
Yosuke TsujiDepartment of Endoscopy and Endoscopic Surgery, The University of Tokyo, Tokyo, Japan.
Tadateru MaehataDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Yasutoshi OchiaiDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Toshihiro NishizawaDepartment of Gastroenterology and Hepatology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Naohisa YahagiDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Keio University · JPGunma University · JPNational Cancer Center Hospital East · JPSt. Marianna University School of Medicine · JPThe University of Tokyo · JPToranomon Hospital · JPTokyo Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients scheduled to undergo oesophageal, gastric and colorectal endoscopic submucosal dissection (ESD) are to be investigated to verify the efficacy of dual red imaging (DRI) for establishing haemostasis during ESD. METHODS AND ANALYSIS: The trial is designed as a multicentre, open-label randomised, parallel-group, controlled intervention study. Registered patients will be randomly assigned to DRI and white light imaging (WLI) groups. In the DRI group, the mucosal incision and submucosal dissection will be performed by WLI, and haemostasis will be managed by DRI when bleeding occurs. In the WLI group, the mucosal incision and submucosal dissection are to be performed by WLI and the haemostasis management is to be performed by WLI. The primary endpoint is the time from the recognition of bleeding up to the achievement of complete haemostasis (haemostasis time). The secondary endpoints are the operation time, the proportion of cases in which perforation occurs, and the psychological stress experienced by the endoscopist during haemostasis treatment. ETHICS AND DISSEMINATION: This trial was approved by the Keio University Review Board for Clinical Trials (5 December 2016). DISCUSSION: This will be the first multicentre collaborative research using DRI for haemostasis treatment during ESD. When the safety and simplicity of DRI as a treatment for haemostasis during ESD can be proven, the ESD procedure can be simplified and disseminated more widely in clinical practice. TRIAL REGISTRATION NUMBER: UMIN000025134.

Indexed as

cancerclinical trialsendoscopic proceduresgastrointestinal haemorrhageimaging

Identifiers

PMID30997140
PMCPMC6441255
OpenAlexW2928632432

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.