Evidence map›Paper›PMID 30997139›Full record

ArticleBMJ open gastroenterology2019

Winston Dunn, Anusha Vittal, Jie Zhao, Jianghua He, Shweta Chakraborty, Melissa Whitener, Sara Fohn, Ryan Ash, Ryan M Taylor, Mojtaba Olyaee and 7 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Winston DunnDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.ORCID 0000-0002-4246-6998
Anusha VittalDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Jie ZhaoDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Jianghua HeDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, Missouri, USA.
Shweta ChakrabortyLiver Transplant Center, University of Kansas Medical Center, Kansas City, Missouri, USA.
Melissa WhitenerDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Sara FohnLiver Transplant Center, University of Kansas Medical Center, Kansas City, Missouri, USA.
Ryan AshDepartment of Diagnostic Radiology, University of Kansas Medical Center, Kansas City, Missouri, USA.
Ryan M TaylorDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Mojtaba OlyaeeDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Jody C OlsonDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Nancy ToddLiver Transplant Center, University of Kansas Medical Center, Kansas City, Missouri, USA.
Beth N FloydDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Prashant PandyaDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
Melissa LaycockLiver Transplant Center, University of Kansas Medical Center, Kansas City, Missouri, USA.
Timothy SchmittDepartment of Surgery, University of Kansas Medical Center, Kansas City, Missouri, USA.
Steven A WeinmanDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Missouri, USA.
University of Kansas Medical Center · US

Funding

Heartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0M
HEARTLAND INSTITUTE FOR CLINICAL AND TRANSLATIONAL RESEARCHUL1RR033179 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2011 to 2011
$3.2M
Factors Responsible for Liver Recovery After Successful Treatment of Hepatitis C.K23DK109294 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI DUNN, WINSTON · 2017 to 2021
$1.0M
NCATS NIH HHS UL1 TR000001NCRR NIH HHS UL1 RR033179NIDDK NIH HHS K23 DK109294
6 · The paper itself

Abstract

backgroundPatients with decompensated hepatitis C virus (HCV) cirrhosis experience various outcomes after sustained virological response (SVR), ranging from clinical recovery to further deterioration. We hypothesised that the genetic risk for steatosis, namely the polymorphisms rs738409 of Patatin-like Phospholipase Domain-Containing 3 (

methodsWe prospectively enrolled 56 patients with Child-Pugh (CPT) B/C cirrhosis who underwent antiviral therapy. The primary outcome was change in CPT score at 12, 24, and 48 weeks after SVR. We used a linear mixed-effects model for analysis.

resultsForty-five patients (

conclusionThe

Indexed as

decompensated cirrhosishepatitis CPNPLA3recovery

Identifiers

PMID30997139
PMCPMC6441264
OpenAlexW2921127015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.