Evidence map›Paper›PMID 30996997›Full record

ArticleChemical science2019

Carrier-free nano-integrated strategy for synergetic cancer anti-angiogenic therapy and phototherapy.

Zheng Wei, Pingping Liang, Junqi Xie, Chuanhui Song, Chuanchao Tang, Yufeng Wang, Xiteng Yin, Yu Cai, Wei Han, Xiaochen Dong

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  20. Dual Size/Charge-Switchable Nanocatalytic Medicine for Deep Tumor Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zheng WeiCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Pingping LiangKey Laboratory of Flexible Electronics (KLOFE) , Institute of Advanced Materials (IAM) , Nanjing Tech University (NanjingTech) , 30 South Puzhu Road , Nanjing , 211800 , China . Email: iamxcdong@njtech.edu.cn.
Junqi XieCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Chuanhui SongCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Chuanchao TangCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Yufeng WangCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.ORCID 0000-0003-2451-7146
Xiteng YinCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Yu CaiCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.ORCID 0000-0001-8669-4418
Wei HanCentral Laboratory of Stomatology , Nanjing Stomatological Hospital , Medical School of Nanjing University , 30 Zhongyang Road , Nanjing , 210008 , China . Email: iamycai@163.com.
Xiaochen DongKey Laboratory of Flexible Electronics (KLOFE) , Institute of Advanced Materials (IAM) , Nanjing Tech University (NanjingTech) , 30 South Puzhu Road , Nanjing , 211800 , China . Email: iamxcdong@njtech.edu.cn.ORCID 0000-0003-4837-9059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, a nano-integrated strategy was used to combine an anti-angiogenic agent sorafenib and a photosensitizer chlorin e6 to form carrier-free multifunctional nanoparticles (SC NPs) for synergetic anti-angiogenic therapy and phototherapy. SC NPs (diameter, ∼152 nm) presented excellent water dispersity and passive targeting ability towards tumor sites

Identifiers

PMID30996997
PMCPMC6419942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.