Evidence map›Paper›PMID 30996965›Full record

ArticleChemical science2019

Ultrasensitive magnetic resonance imaging of systemic reactive oxygen species

Huan Wang, Dongqin Yu, Bo Li, Zhen Liu, Jinsong Ren, Xiaogang Qu

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  7. Toward quantification of hypoxia using fluorinated EuProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
  9. Article
  10. [Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Article
  11. Review
  12. Nanotools for Sepsis Diagnosis and Treatment.Advanced healthcare materials · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Huan WangState Key Laboratory of Rare Earth Resources Utilization , Laboratory of Chemical Biology , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , 130022 , P. R. China . Email: jren@ciac.ac.cn ; Email: xqu@ciac.ac.cn.
Dongqin YuState Key Laboratory of Rare Earth Resources Utilization , Laboratory of Chemical Biology , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , 130022 , P. R. China . Email: jren@ciac.ac.cn ; Email: xqu@ciac.ac.cn.
Bo LiDepartment of Radiology , The Second Hospital of Jilin University , Changchun , Jilin 130041 , P. R. China.
Zhen LiuState Key Laboratory of Rare Earth Resources Utilization , Laboratory of Chemical Biology , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , 130022 , P. R. China . Email: jren@ciac.ac.cn ; Email: xqu@ciac.ac.cn.
Jinsong RenState Key Laboratory of Rare Earth Resources Utilization , Laboratory of Chemical Biology , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , 130022 , P. R. China . Email: jren@ciac.ac.cn ; Email: xqu@ciac.ac.cn.ORCID 0000-0002-7506-627X
Xiaogang QuState Key Laboratory of Rare Earth Resources Utilization , Laboratory of Chemical Biology , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , 130022 , P. R. China . Email: jren@ciac.ac.cn ; Email: xqu@ciac.ac.cn.ORCID 0000-0003-2868-3205
Chinese Academy of Sciences · CNUniversity of Science and Technology of China · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current diagnostic methods for sepsis lack required speed or precision, often failing to make timely accurate diagnosis for early medical treatment. The systemic excess generation of reactive oxygen species (ROS) during sepsis has been considered as an early indicator of sepsis. Herein, we present the rational design of novel activatable nanoprobes (ROS CAs) composed of a clinically approved iron oxide core, Gd-DTPA, and hyaluronic acid (HA) that can image ROS down to sub-micromolar concentrations

Identifiers

PMID30996965
PMCPMC6447818
OpenAlexW2917653726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.