Evidence map›Paper›PMID 30996923›Full record

ArticleChemical science2019

Reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis.

Rick C Betori, Benjamin R McDonald, Karl A Scheidt

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 30 citations in OpenAlex.

  1. Reductive Cross-Coupling of Olefins via a Radical Pathway.Journal of the American Chemical Society · 2023
    Article
  2. Review
  3. Ball-Milling-Enabled Reactivity of Manganese Metal*.Angewandte Chemie (International ed. in English) · 2021
    Article
  4. High-throughput photocapture approach for reaction discovery.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Article
  6. Radical coupling ofGreen synthesis and catalysis · 2020
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rick C BetoriDepartment of Chemistry , Center for Molecular Innovation and Drug Discovery , Northwestern University , 2145 Sheridan Road , Evanston , Illinois 60208 , USA . Email: Scheidt@northwestern.edu.
Benjamin R McDonaldDepartment of Chemistry , Center for Molecular Innovation and Drug Discovery , Northwestern University , 2145 Sheridan Road , Evanston , Illinois 60208 , USA . Email: Scheidt@northwestern.edu.
Karl A ScheidtDepartment of Chemistry , Center for Molecular Innovation and Drug Discovery , Northwestern University , 2145 Sheridan Road , Evanston , Illinois 60208 , USA . Email: Scheidt@northwestern.edu.ORCID 0000-0003-4856-3569
Northwestern University · US

Funding

Supplement to Carbene Catalysis Strategies for Organic SynthesisR01GM073072 · NIGMS · NORTHWESTERN UNIVERSITY · PI SCHEIDT, KARL A · 2006 to 2018
$4.0M
Chemistry of Life Processes Predoctoral Training ProgramT32GM105538 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2013 to 2022
$2.7M
Exploration of Novel Silyl Derived d1 Synthon EquivalentsF31GM116532 · NIGMS · NORTHWESTERN UNIVERSITY · PI MCDONALD, BENJAMIN REBBECK · 2015 to 2017
$112k
NIGMS NIH HHS F31 GM116532NIGMS NIH HHS R01 GM073072NIGMS NIH HHS T32 GM105538
6 · The paper itself

Abstract

A cooperative Lewis acid/photocatalytic reduction of salicylaldehyde-derived arylidene malonates provides access to a versatile, stabilized radical anion enolate. Using these unusual umpolung operators, we have developed a novel route to access densely functionalized carbo- and heterocycles through a radical annulation addition pathway.

Identifiers

PMID30996923
PMCPMC6430011
OpenAlexW2913507110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.