Evidence map›Paper›PMID 30996904›Full record

ArticleChemical science2019

Catalytic radical difluoromethoxylation of arenes and heteroarenes.

Johnny W Lee, Weijia Zheng, Cristian A Morales-Rivera, Peng Liu, Ming-Yu Ngai

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. C-H Fluoromethoxylation of Arenes by Photoredox Catalysis.Angewandte Chemie (International ed. in English) · 2023
    Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Johnny W LeeDepartment of Chemistry , Institute of Chemical Biology and Drug Discovery , Stony Brook University , Stony Brook , NY 11794 , USA . Email: ming-yu.ngai@stonybrook.edu.ORCID 0000-0002-0950-7815
Weijia ZhengDepartment of Chemistry , Institute of Chemical Biology and Drug Discovery , Stony Brook University , Stony Brook , NY 11794 , USA . Email: ming-yu.ngai@stonybrook.edu.ORCID 0000-0003-0170-4088
Cristian A Morales-RiveraDepartment of Chemistry , University of Pittsburgh , Pittsburgh , PA 15260 , USA . Email: pengliu@pitt.edu.
Peng LiuDepartment of Chemistry , University of Pittsburgh , Pittsburgh , PA 15260 , USA . Email: pengliu@pitt.edu.ORCID 0000-0002-8188-632X
Ming-Yu NgaiDepartment of Chemistry , Institute of Chemical Biology and Drug Discovery , Stony Brook University , Stony Brook , NY 11794 , USA . Email: ming-yu.ngai@stonybrook.edu.ORCID 0000-0002-3055-6662

Funding

Novel Strategies and Reagents for Introduction of Fluorinated GroupsR35GM119652 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI Ming-Yu Ngai · 2016 to 2026
$4.8M
NIGMS NIH HHS R35 GM119652
6 · The paper itself

Abstract

Intermolecular C-H difluoromethoxylation of (hetero)arenes remains a long-standing and unsolved problem in organic synthesis. Herein, we report the first catalytic protocol employing a redox-active difluoromethoxylating reagent

Identifiers

PMID30996904
PMCPMC6429774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.