ArticleChemical science2019
One fold, two functions: cytochrome P460 and cytochrome
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Article
- Cytochromes P460 and c'-β: exploiting a novel fold for multiple functions.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025Review
- Conformational rigidity of cytochrome c'-α from a thermophile is associated with slow NO binding.Biophysical journal · 2024Article
- The H-NOX protein structure adapts to different mechanisms in sensors interacting with nitric oxide.Chemical science · 2023Article
- Cytochrome P460 Cofactor Maturation Proceeds via Peroxide-Dependent Post-translational Modification.Journal of the American Chemical Society · 2023Article
- A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-β: Implications for NO sensors.The Journal of biological chemistry · 2023Article
- Crystal structure of thermally stable homodimeric cytochrome c'-β from Thermus thermophilus.Acta crystallographica. Section F, Structural biology communications · 2022Article
- Biological and Bioinspired Inorganic N-N Bond-Forming Reactions.Chemical reviews · 2020Review
- High Synteny and Sequence Identity between Genomes ofMicroorganisms · 2020Article
Corrections and comments
- Erratum issuedCorrection: One fold, two functions: cytochrome P460 and cytochrome c'-β from the methanotroph2019 · Moreno T [corrected to Moreno-Chicano T]
- Erratum issued
Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nature is adept at utilising highly similar protein folds to carry out very different functions, yet the mechanisms by which this functional divergence occurs remain poorly characterised. In certain methanotrophic bacteria, two homologous pentacoordinate c-type heme proteins have been identified: a cytochrome P460 (cyt P460) and a cytochrome
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.