Evidence map›Paper›PMID 30996873›Full record

ArticleChemical science2019

Light emission enhancement by supramolecular complexation of chemiluminescence probes designed for bioimaging.

Samer Gnaim, Anna Scomparin, Anat Eldar-Boock, Christoph R Bauer, Ronit Satchi-Fainaro, Doron Shabat

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Supramolecular Mitigation of the Cyanine Limit Problem.The Journal of organic chemistry · 2022
    Article
  11. Chemiluminescent 1,2-Dioxetane Iridium Complexes for Near-Infrared Oxygen Sensing.Angewandte Chemie (International ed. in English) · 2022
    Article
  12. Article
  13. Prevent or Cure-The Unprecedented Need for Self-Reporting Materials.Angewandte Chemie (International ed. in English) · 2021
    Review
  14. Coal-Tar Dye-based Coordination Cages and Helicates.Angewandte Chemie (International ed. in English) · 2021
    Article
  15. Review
  16. Self-Illuminating Agents for Deep-Tissue Optical Imaging.Frontiers in bioengineering and biotechnology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 4 countries.

Samer GnaimSchool of Chemistry , Raymond and Beverly Sackler Faculty of Exact Sciences , Israel . Email: chdoron@tauex.tau.ac.il.
Anna ScomparinDepartment of Physiology and Pharmacology , Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv 69978 , Israel.ORCID 0000-0003-4751-620X
Anat Eldar-BoockDepartment of Physiology and Pharmacology , Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv 69978 , Israel.ORCID 0000-0002-8716-4328
Christoph R BauerBioimaging Center , University of Geneva , Geneva , Switzerland.
Ronit Satchi-FainaroDepartment of Physiology and Pharmacology , Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv 69978 , Israel.ORCID 0000-0002-7360-7837
Doron ShabatSchool of Chemistry , Raymond and Beverly Sackler Faculty of Exact Sciences , Israel . Email: chdoron@tauex.tau.ac.il.ORCID 0000-0003-2502-639X
Tel Aviv University · ILUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemiluminescence offers advantages over fluorescence for bioimaging, since an external light source is unnecessary with chemiluminescent agents. This report demonstrates the first encapsulation of chemiluminescence phenoxy-adamantyl-1,2-dioxetane probes with trimethyl β-cyclodextrin. Clear proof for the formation of a 1 : 1 host-guest complex between the adamantyl-1,2-dioxetane probe and trimethyl β-cyclodextrin was provided by mass spectroscopy and NMR experiments. The calculated association constant of this host-guest system, 253 M

Identifiers

PMID30996873
PMCPMC6427943
OpenAlexW2911092974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.