Evidence map›Paper›PMID 30996857›Full record

ArticleMedChemComm2019

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity.

Ana C S Gondim, Suzete Roberta da Silva, Leen Mathys, Sam Noppen, Sandra Liekens, Alexandre Holanda Sampaio, Celso S Nagano, Cintia Renata Costa Rocha, Kyria S Nascimento, Benildo S Cavada and 2 more

Open access · hybridAbstract read
In one paragraph

Article in MedChemComm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  7. Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
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  9. Review
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  11. Review
  12. Antimicrobial agents and chemotherapy · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Ana C S GondimDepartment of Biochemistry and Molecular Biology , Federal University of Ceará , 60455-760 , Fortaleza , Ceará , Brazil . Email: bscavada@gmail.com.ORCID 0000-0003-3526-1203
Suzete Roberta da SilvaDepartment of Fishing and Engineering , Federal University of Ceará , 60455-900 , Fortaleza , Ceará , Brazil.ORCID 0000-0002-6254-1975
Leen MathysRega Institute for Medical Research , Department of Microbiology and Immunology , KU Leuven , 3000 Leuven , Belgium . Email: jan.balzarini@kuleuven.be.ORCID 0000-0002-5123-8751
Sam NoppenRega Institute for Medical Research , Department of Microbiology and Immunology , KU Leuven , 3000 Leuven , Belgium . Email: jan.balzarini@kuleuven.be.ORCID 0000-0002-2831-5042
Sandra LiekensRega Institute for Medical Research , Department of Microbiology and Immunology , KU Leuven , 3000 Leuven , Belgium . Email: jan.balzarini@kuleuven.be.ORCID 0000-0002-3529-8121
Alexandre Holanda SampaioDepartment of Fishing and Engineering , Federal University of Ceará , 60455-900 , Fortaleza , Ceará , Brazil.ORCID 0000-0003-3871-0502
Celso S NaganoDepartment of Fishing and Engineering , Federal University of Ceará , 60455-900 , Fortaleza , Ceará , Brazil.ORCID 0000-0001-5988-5868
Cintia Renata Costa RochaBiochemistry Department , LINKA/UFPE , CEP 50670-901 , Recife , Pernambuco , Brazil.ORCID 0000-0002-3366-3615
Kyria S NascimentoDepartment of Biochemistry and Molecular Biology , Federal University of Ceará , 60455-760 , Fortaleza , Ceará , Brazil . Email: bscavada@gmail.com.ORCID 0000-0002-2220-4552
Benildo S CavadaDepartment of Biochemistry and Molecular Biology , Federal University of Ceará , 60455-760 , Fortaleza , Ceará , Brazil . Email: bscavada@gmail.com.ORCID 0000-0002-5791-6170
Peter J SadlerDepartment of Chemistry , University of Warwick , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.ORCID 0000-0001-9160-1941
Jan BalzariniRega Institute for Medical Research , Department of Microbiology and Immunology , KU Leuven , 3000 Leuven , Belgium . Email: jan.balzarini@kuleuven.be.ORCID 0000-0003-1144-1808
Universidade Federal do Ceará · BRRega Institute for Medical Research · BEUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brazil has one of the largest biodiversities in the world. The search for new natural products extracted from the Brazilian flora may lead to the discovery of novel drugs with potential to treat infectious and other diseases. Here, we have investigated 9 lectins extracted and purified from the Northeastern Brazilian flora, from both leguminous species:

Identifiers

PMID30996857
PMCPMC6430086
OpenAlexW2908751260

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.