Evidence map›Paper›PMID 30996782›Full record

ArticleACS medicinal chemistry letters2019

First-of-its-kind STARD

Margherita Lapillo, Barbara Salis, Stefano Palazzolo, Giulio Poli, Carlotta Granchi, Filippo Minutolo, Rossella Rotondo, Isabella Caligiuri, Vincenzo Canzonieri, Tiziano Tuccinardi and 1 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Organelle contact sites in cancer cells.Cell death & disease · 2026
    Review
  5. 27-Hydroxycholesterol in cancer development and drug resistance.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  6. [Multi-omics analysis of the relationship between oxidative stress-related gene and prostate cancer].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  7. Watermelon: setup and validation of anJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  8. Article
  9. Article
  10. Is STARD3 A New Biomarker for Breast Cancer?European journal of breast health · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Differential Expression and Prognostic Significance of STARD3 Gene in Breast Carcinoma.International journal of molecular and cellular medicine · 2021
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Margherita LapilloDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Barbara SalisDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
Stefano PalazzoloDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
Giulio PoliDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Carlotta GranchiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Filippo MinutoloDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Rossella RotondoDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
Isabella CaligiuriDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
Vincenzo CanzonieriDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
Tiziano TuccinardiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Flavio RizzolioDepartment of Translational Research, Pathology Unit, National Cancer Institute-CRO-IRCSS, 33081 Aviano, Italy.
University of Pisa · ITCentro di Riferimento Oncologico · ITCa' Foscari University of Venice · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STARD3 is a cellular protein that represents an attractive target for cancer therapy, being overexpressed in breast cancer and implied in the development of colorectal, gastric, and prostate cancers. Unfortunately, no STARD3 inhibitor has been identified yet. In this work, an

Identifiers

PMID30996782
PMCPMC6466518
OpenAlexW2916749426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.