Evidence map›Paper›PMID 30996779›Full record

ArticleACS medicinal chemistry letters2019

Discovery of Pyrido[3',2':5,6]thiopyrano[4,3-

Silvia Salerno, Elisabetta Barresi, Aída Nelly García-Argáez, Sabrina Taliani, Francesca Simorini, Giorgio Amendola, Stefano Tomassi, Sandro Cosconati, Ettore Novellino, Federico Da Settimo and 2 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Silvia SalernoDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Elisabetta BarresiDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Aída Nelly García-ArgáezDipartimento di Scienze del Farmaco, Università di Padova, Via Marzolo 5, 35131 Padova, Italy.
Sabrina TalianiDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Francesca SimoriniDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Giorgio AmendolaDiSTABiF, Università della Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Stefano TomassiDiSTABiF, Università della Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Sandro CosconatiDiSTABiF, Università della Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Ettore NovellinoDipartimento di Farmacia, Università di Napoli "Federico II", Via D. Montesano 49, 80131 Napoli, Italy.
Federico Da SettimoDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Anna Maria MariniDipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Lisa Dalla ViaDipartimento di Scienze del Farmaco, Università di Padova, Via Marzolo 5, 35131 Padova, Italy.
University of Pisa · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Padua · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein kinases dysregulation is extremely common in cancer cells, and the development of new agents able to simultaneously target multiple kinase pathways involved in angiogenesis and tumor growth may offer several advantages in the treatment of cancer. Herein we report the discovery of new pyridothiopyranopyrimidine derivatives (

Identifiers

PMID30996779
PMCPMC6466516
OpenAlexW2908649222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.