Evidence map›Paper›PMID 30996682›Full record

ArticleReproductive medicine and biology2019

Oocyte collection and in vitro maturation after train transportation of human follicular fluid aspirated from resected non-stimulated ovaries of patients with endometrial adenocarcinoma.

Hiromitsu Shirasawa, Natsuki Ono, Yukiyo Kumazawa, Wataru Sato, Naoki Sato, Motomasa Ihara, Nobuo Yaegashi, Yukihiro Terada

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hiromitsu ShirasawaDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.ORCID https://orcid.org/0000-0001-5300-0037
Natsuki OnoDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.ORCID https://orcid.org/0000-0002-7727-1736
Yukiyo KumazawaDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.
Wataru SatoDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.
Naoki SatoDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.
Motomasa IharaDepartment of Obstetrics and Gynecology Tohoku University Graduate School of Medicine Sendai Japan.
Nobuo YaegashiDepartment of Obstetrics and Gynecology Tohoku University Graduate School of Medicine Sendai Japan.
Yukihiro TeradaDepartment of Obstetrics and Gynecology Akita University Graduate School of Medicine Akita Japan.
Akita University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImmature human oocytes from resected ovaries can be used for research and fertility preservation, though it is unknown whether it is feasible to transport oocytes for these purposes. This study examined in vitro maturation (IVM) outcomes after the transportation of human follicular fluid (HFF) containing oocytes.

methodsFourteen patients with endometrial adenocarcinoma were enrolled. Oocytes obtained from the resected ovaries of seven patients were transported with HFF by railway (transportation group). Samples of HFF from the other seven patients were not transported, and IVM was performed promptly (non-transportation group). The results of oocyte retrieval and IVM were compared.

resultsThe average ages in the transportation and non-transportation groups were 40.1 ± 2.0 and 39.6 ± 1.8 years, respectively, and the average numbers of collected oocytes were 8.1 ± 8.4 and 5.1 ± 5.1, respectively. There was a significant negative correlation between the number of collected oocytes and age. The proportions of oocytes that reached meiosis II (maturation rate) after IVM were 38.6% and 69.2% in the transportation and non-transportation groups, respectively (

conclusionIn this preliminary study, the usefulness of the transportation of HFF was limited. Further studies on maintaining oocyte normality during transportation are necessary for becoming the effective method for research and clinical use.

Indexed as

follicular fluidimmature human oocytesin vitro maturationoncofertilitytransportation

Identifiers

PMID30996682
PMCPMC6452027
OpenAlexW2910662285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.