Evidence map›Paper›PMID 30996603›Full record

ArticlePaediatrics & child health2019

Is NSAID use in children associated with the risk of renal injury?

Amrit Kirpalani, Michael Rieder

Open access · greenAbstract read
In one paragraph

Article in Paediatrics & child health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Amrit KirpalaniDepartment of Paediatrics, Children's Hospital/London Health Sciences Centre, Schulich School of Medicine & Dentistry, Western University, London, Ontario.
Michael RiederDepartment of Paediatrics, Children's Hospital/London Health Sciences Centre, Schulich School of Medicine & Dentistry, Western University, London, Ontario.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal injury is known to be a risk of nonsteroidal anti-inflammatory drug (NSAID) therapy in adults. While this appears to be much less common in children, there are some groups of children who do appear to be at risk of renal injury associated with NSAID therapy and clinicians caring for these patients need to be cognizant of this potential risk.

Indexed as

ChildrenDrug safetyNSAIDsRenal injury

Identifiers

PMID30996603
PMCPMC6462120
OpenAlexW4206760205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.