Evidence map›Paper›PMID 30996294›Full record

ReviewNature reviews. Endocrinology2019

A new strategy for vascular complications in young people with type 1 diabetes mellitus.

M Loredana Marcovecchio, R Neil Dalton, Denis Daneman, John Deanfield, Timothy W Jones, H Andrew W Neil, David B Dunger, Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT) study group

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Aerobic Exercise Ameliorates Adverse Vascular Remodeling in Diabetes via PDK1/FoxO1 Axis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M Loredana MarcovecchioDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
R Neil DaltonGuy's and St Thomas' NHS Foundation Trust, London, UK.
Denis DanemanDepartment of Paediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
John DeanfieldVascular Physiology Unit, Institute of Cardiovascular Science, University College London, London, UK.
Timothy W JonesTelethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.
H Andrew W NeilOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
David B DungerDepartment of Paediatrics, University of Cambridge, Cambridge, UK. dbd25@cam.ac.uk.ORCID http://orcid.org/0000-0002-2566-9304
Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT) study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes vascular complications, including cardiovascular disease, diabetic nephropathy and retinopathy, have a negative effect on the long-term prognosis of young people with type 1 diabetes mellitus (T1DM). Poor glycaemic control and consequent increased HbA

Indexed as

Glycemic IndexAdolescentAge FactorsBlood GlucoseChildChild, PreschoolDiabetes Mellitus, Type 1FemaleFollow-Up StudiesHumansInsulinMaleSeverity of Illness IndexBlood GlucoseInsulin

Identifiers

PMID30996294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.