Evidence map›Paper›PMID 30996290›Full record

ArticleScientific reports2019

De Novo Transcriptome Assembly and Functional Annotation in Five Species of Bats.

Diana D Moreno-Santillán, Carlos Machain-Williams, Georgina Hernández-Montes, Jorge Ortega

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Full-Length Transcriptome of the Great Himalayan Leaf-Nosed Bats (International journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Insights into the species evolution ofEcology and evolution · 2022
    Article
  17. Genes · 2021
    Article
  18. Article
  19. Diversification of mammalian deltaviruses by host shifting.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. PeerJ · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Diana D Moreno-SantillánEscuela Nacional de Ciencias Biológicas, Posgrado Químicobiológicas, Instituto Politécnico Nacional, Departamento de Zoología, Ciudad de México, CDMX, Mexico.
Carlos Machain-WilliamsCentro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Laboratorio de Arbovirología, Mérida, Yucatán, Mexico.
Georgina Hernández-MontesUniversidad Nacional Autónoma de México, Red de Apoyo a la Investigación, Ciudad de México, CDMX, Mexico.
Jorge OrtegaEscuela Nacional de Ciencias Biológicas, Posgrado Químicobiológicas, Instituto Politécnico Nacional, Departamento de Zoología, Ciudad de México, CDMX, Mexico. artibeus2@aol.com.
Instituto Politécnico Nacional · MXAutonomous University of Yucatán · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput RNA sequencing is a powerful tool that allows us to perform gene prediction and analyze tissue-specific overexpression of genes, but also at species level comparisons can be performed, although in a more restricted manner. In the present study complete liver transcriptomes of five tropical bat species were De novo assembled and annotated. Highly expressed genes in the five species were involved in glycolysis and lipid metabolism pathways. Cross-species differential expression analysis was conducted using single copy orthologues shared across the five species. Between 22 and 29 orthologs were upregulated for each species. We detected upregulated expression in Artibeus jamaicensis genes related to fructose metabolism pathway. Such findings can be correlated with A. jamaicensis dietary habits, as it was the unique frugivorous species included. This is the first report of transcriptome assembly by RNA-seq in these species, except for A. jamaicensis and as far as our knowledge is the first cross-species comparisons of transcriptomes and gene expression in tropical bats.

Indexed as

Molecular Sequence AnnotationTranscriptomeAnimalsChiropteraGene ExpressionGene Expression ProfilingGlycolysisHigh-Throughput Nucleotide SequencingLipid MetabolismLiverPhylogenyRNA-SeqSequence Analysis, RNA

Identifiers

PMID30996290
PMCPMC6470166
OpenAlexW2936594259

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.