ArticleScientific reports2019
Disentangling host-parasite-pathogen interactions in a varroa-resistant honeybee population reveals virus tolerance as an independent, naturally adapted survival mechanism.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 46 citations in OpenAlex.
- Experimental infection of acute bee paralysis virus induces differential responses of selected honey bee immune genes, independent of varroa resistance.Scientific reports · 2026Article
- Evidence for virus-associated recapping behaviour in honey bees (Apis mellifera) with differential detection sensitivity between varroa-resistant and non-resistant colonies.Scientific reports · 2026Article
- Mechanical transfer of honey bee (Hymenoptera: Apidae) virus sequences to wax by worker traffic and aerosolization.Journal of insect science (Online) · 2025Article
- Avoiding the tragedies of parasite tolerance in Darwinian beekeeping.Proceedings. Biological sciences · 2025Review
- Origins, diversity, and adaptive evolution of DWV in the honey bees of the Azores: the impact of the invasive miteVirus evolution · 2024Article
- A preliminary survey reveals that common viruses are found at low titers in a wild population of honey bees (Apis mellifera).Journal of insect science (Online) · 2023Article
- Signatures of adaptive decreased virulence of deformed wing virus in an isolated population of wild honeybees (Proceedings. Biological sciences · 2023Article
- Honey Bee Larval Hemolymph as a Source of Key Nutrients and Proteins Offers a Promising Medium forInternational journal of molecular sciences · 2023Article
- Expression of Molecular Markers of Resilience againstInsects · 2023Article
- Virus infections in honeybee colonies naturally surviving ectoparasitic mite vectors.PloS one · 2023Article
- Virus Prevalence in Egg Samples Collected from Naturally Selected and Traditionally Managed Honey Bee Colonies across Europe.Viruses · 2022Article
- Signatures of Positive Selection in the Genome ofLife (Basel, Switzerland) · 2022Article
- Viral species differentially influence macronutrient preferences based on honey bee genotype.Biology open · 2022Article
- A derived honey bee stock confers resistance to Varroa destructor and associated viral transmission.Scientific reports · 2022Article
- Honey Bee Genetic Stock Determines Deformed Wing Virus Symptom Severity but not Viral Load or Dissemination Following Pupal Exposure.Frontiers in genetics · 2022Article
- Field evaluation of Varroa-resistance traits in surviving Apis mellifera colonies in Argentina.Parasitology research · 2021Article
- Global similarity, and some key differences, in the metagenomes of Swedish varroa-surviving and varroa-susceptible honeybees.Scientific reports · 2021Article
- Multi-tiered analyses of honey bees that resist or succumb to parasitic mites and viruses.BMC genomics · 2021Article
- Parallel evolution ofProceedings. Biological sciences · 2021Article
- Adapted tolerance to virus infections in four geographically distinct Varroa destructor-resistant honeybee populations.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ectoparasitic mite, Varroa destructor, is unarguably the leading cause of honeybee (Apis mellifera) mortality worldwide through its role as a vector for lethal viruses, in particular, strains of the Deformed wing virus (DWV) and Acute bee paralysis virus (ABPV) complexes. This multi-level system of host-parasite-pathogen interactions makes it difficult to investigate effects of either the mite or the virus on natural host survival. The aim of this study was to remove confounding effects of varroa to examine the role of virus susceptibility in the enhanced survival of a naturally adapted Swedish mite-resistant (MR) honeybee population, relative to mite-susceptible (MS) honeybees. Caged adult bees and laboratory reared larvae, from varroa-free colonies, were inoculated with DWV and ABPV in a series of feeding infection experiments, while control groups received virus-free food. Virus infections were monitored using RT-qPCR assays in individuals sampled over a time course. In both adults and larvae the DWV and ABPV infection dynamics were nearly identical between MR and MS groups, but MS adults suffered significantly higher mortality than MR adults. Results suggest virus tolerance, rather than reduced susceptibility or virus resistance, is an important component of the natural survival of this honeybee population.
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