Evidence map›Paper›PMID 30996175›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Oligosecretory Primary Plasma Cell Leukemia with Atypical Morphological Abnormality.

Eo Toriyama, Yoshitaka Imaizumi, Kazuto Tsuruda, Hidehiro Itonaga, Shinya Sato, Koji Ando, Yasushi Sawayama, Hiroo Hasegawa, Tomoko Hata, Daisuke Niino and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Chromogenic in situ hybridization for the detection of lambda and kappa immunoglobulin light chains as a potential auxiliary diagnostic technique in canine plasmacytomas.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Eo ToriyamaDepartment of Hematology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Yoshitaka ImaizumiDepartment of Hematology, Nagasaki University Hospital, Japan.
Kazuto TsurudaDepartment of Laboratory Medicine, Nagasaki University Hospital, Japan.
Hidehiro ItonagaDepartment of Hematology, Nagasaki University Hospital, Japan.
Shinya SatoDepartment of Hematology, Nagasaki University Hospital, Japan.
Koji AndoDepartment of Hematology, Nagasaki University Hospital, Japan.
Yasushi SawayamaDepartment of Hematology, Nagasaki University Hospital, Japan.
Hiroo HasegawaDepartment of Laboratory Medicine, Nagasaki University Hospital, Japan.
Tomoko HataDepartment of Hematology, Nagasaki University Hospital, Japan.
Daisuke NiinoDepartment of Nagasaki Educational-Diagnostic Center of Pathology, Nagasaki University, Japan.
Katsunori YanagiharaDepartment of Laboratory Medicine, Nagasaki University Hospital, Japan.
Yasushi MiyazakiDepartment of Hematology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Nagasaki University Hospital · JPNagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma cell leukemia (PCL) is a rare variant of multiple myeloma. The detection of plasma cells in the peripheral blood and monoclonal protein in the serum or urine is important for the diagnosis of PCL. However, it is sometimes difficult to diagnose PCL in patients with atypical plasma cell morphology and/or those without detectable monoclonal protein. We herein report a case of oligosecretory PCL showing atypical morphology in leukemic cells with a convoluted nucleus and basophilic cytoplasm but without detectable monoclonal protein, except for serum free light chain. A flow cytometric analysis and pathological analysis were useful for the early diagnosis of PCL.

Indexed as

Aged, 80 and overCytoplasmFlow CytometryHumansImmunoglobulin Light ChainsLeukemia, Plasma CellMaleMyeloma ProteinsPlasma CellsImmunoglobulin Light Chainsmultiple myeloma M-proteinsMyeloma Proteinsatypical morphologynon-secretory typeoligosecretory typeprimary plasma cell leukemia

Identifiers

PMID30996175
PMCPMC6709312
OpenAlexW2936663830

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.