Evidence map›Paper›PMID 30996157›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Autoimmune Pulmonary Alveolar Proteinosis Diagnosed after Exposure to a Fire Extinguisher Containing Silica Powder.

Takafumi Yorozuya, Kimiyuki Ikeda, Hirofumi Chiba, Atsushi Saito, Koji Kuronuma, Hirotaka Nishikiori, Satsuki Miyajima, Mamoru Takahashi, Takumi Yoshikawa, Youhei Takahashi and 6 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A comprehensive summary of disease variants implicated in metal allergy.Journal of toxicology and environmental health. Part B, Critical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Takafumi YorozuyaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Kimiyuki IkedaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Hirofumi ChibaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Atsushi SaitoDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Koji KuronumaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Hirotaka NishikioriDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Satsuki MiyajimaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Mamoru TakahashiDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Takumi YoshikawaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Youhei TakahashiDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Tetsuya TayaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Yuki MoriDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Yasuaki UmedaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Mitsuo OtsukaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Hiroshi MoriyamaDepartment of Respiratory Medicine, Nishi-Niigata Chuo National Hospital, Japan.
Hiroki TakahashiDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Sapporo Medical University · JPNishi Niigata Chuo National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of autoimmune pulmonary alveolar proteinosis (PAP) diagnosed after one-time exposure to silica powder. Owing to the misuse of a silica-containing fire extinguisher and the inhalation of large amounts of its powder, the patient experienced prolonged cough and visited our hospital. The findings of chest computed tomography and surgical lung biopsy specimens led to the diagnosis of PAP. Interestingly, the presence of anti-GM-CSF antibody was detected; therefore, both autoimmune characteristics and exposure to large amounts of silica may have caused the development of PAP in this patient. This case provides important insight into the mechanisms leading to the onset of PAP.

Indexed as

Administration, InhalationAgedAutoimmune DiseasesEnvironmental ExposureFemaleFire Extinguishing SystemsHumansParticulate MatterPulmonary Alveolar ProteinosisSilicon DioxideParticulate MatterSilicon Dioxideanti-GM-CSF antibodydustelemental analysisfire extinguisherpulmonary alveolar proteinosissilica

Identifiers

PMID30996157
PMCPMC6702020
OpenAlexW2935857045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.