Evidence map›Paper›PMID 30996090›Full record

ArticleJournal of virology2019

Phenotypic and Functional Differences between Human Herpesvirus 6- and Human Cytomegalovirus-Specific T Cells.

Solène Fastenackels, Charles Bayard, Martin Larsen, Philippe Magnier, Pascale Bonnafous, Nabila Seddiki, Victor Appay, Agnès Gautheret-Dejean, Delphine Sauce

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Evasion of the Host Immune Response by Betaherpesviruses.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Solène FastenackelsINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Charles BayardINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Martin LarsenINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Philippe MagnierINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Pascale BonnafousINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Nabila SeddikiINSERM U955, équipe 16, Vaccine Research Institute, Faculté de Médecine, Université Paris Est Créteil, Créteil, France.
Victor AppayINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.
Agnès Gautheret-DejeanAPHP, Hospital Pitié-Salpêtrière Paris, Laboratory of Virology, Paris, France.
Delphine SauceINSERM 1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France delphine.sauce@upmc.fr.
Centre d'Immunologie et des Maladies Infectieuses · FRInserm · FRInstitut de Recherche Vaccinale · FRPitié-Salpêtrière Hospital · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human herpesvirus 6 (HHV-6) infects >90% of the population and establishes a latent infection with asymptomatic episodes of reactivation. However, HHV-6 reactivation is associated with morbidity and sometimes mortality in immunocompromised patients. To date, control of the virus in healthy virus carriers and the failure to control it in patients with disease remain poorly understood. In particular, knowledge of HHV-6-specific T-cell responses is limited. Here, we characterized HHV-6A- and HHV-6B-specific CD4

Indexed as

AdolescentAdultCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytomegalovirusCytomegalovirus InfectionsHerpesvirus 6, HumanHumansLeukocytes, MononuclearMiddle AgedParisPhenotypeRoseolovirus InfectionsT-Lymphocytes, RegulatoryYoung Adulteffector T cellsHCMVHHV-6regulatory T cells

Identifiers

PMID30996090
PMCPMC6580948
OpenAlexW2937020839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.